TABLE 4.
Conservation of the N-linked glycosylation sites on influenza virus H3 HAs from 1968 to 2018a
| HA residue numbering of N-glycosylation motif | N-linked glycosylation site (% conservation) | Comment |
|---|---|---|
| 63 x 65 | N(99) x T(100) | Clear glycan density |
| 122 x 124 | N(95)/D(3) x S(92)/G(4)/D(3) | No glycan density |
| 126 x 128 | N(97) x T(87)/A(12) | Not glycosylation site in Sw/13 HA |
| 133 x 135 | N(94)/D(4) x T(90) | Clear glycan density |
| 144 x 146 | N(48)/S(33) x S(99) | No glycan density |
| 158 x 160 | N(70)/K(22) x K(63)/T(34) | Not glycosylation site in Sw/13 HA |
| 165 x 167 | N(100) x T(100) | Clear glycan density |
| 246 x 248 | N(99) x T(98) | Clear glycan density |
a
Residues at each N-linked glycosylation sites are listed with percent identity for most common residue(s), where the N-glycosylation motif is Asn-x-Ser/Thr (x can be any residue other than proline).