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Biolayer interferometry binding studiesa
| Sample | bnmAb | Mean KD (pM) (SE) | Mean ka (105 M−1 s−1) (SE) | Mean kd (10−4 s−1) (SE) | R2 |
|---|---|---|---|---|---|
| RSV Gecto | 3D3 | 202 (±1) | 8.73 (±0.02) | 1.77 (±0.01) | 0.998 |
| RSV Gecto F170P | 3D3 | 264 (±1) | 6.23 (±0.01) | 1.65 (±0.01) | 0.999 |
| RSV Gecto | 3G12 | 423 (±1) | 5.27 (±0.01) | 2.23 (±0.01) | 0.999 |
| RSV Gecto F170P | 3G12 | NB |
KD, binding dissociation constant; ka, on-rate; kd, off-rate; R2, curve fit statistic; NB, no binding observed. Values in parentheses are standard errors.
