FIG 7.

Apoptotic effect of CD80 on the presence or absence of LAT in the TG of latently infected mice. TG from latently infected HSV-CD80 [LAT(−)] and McKrae [LAT(+)] mice were individually isolated on day 28 p.i., and qRT-PCR was performed using total RNA as described in Materials and Methods. Caspase 3 (Casp 3), caspase 8, caspase 9, and Bcl2 fold gene expression was assessed for each group of mice. GAPDH expression was used to normalize the relative expression of each transcript. Each point represents the mean ± SEM from 10 TG.