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DP reduces VEGF and HIF-1a expression in vivo. Immunohistochemical analysis of tumors from Hepa1-6 and H22 tumor-bearing mice. (A, C) Thetumor sections were subjected to IHC staining using an antibody against VEGF. (B, D) The tumor sections were subjected to IHC staining using an antibody against IGF-1a. *P < 0.05, **P < 0.01.
