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. 2020 Apr 15;10:40. doi: 10.1186/s13613-020-00659-7

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Frequency of the variables utilized as criteria of hypoperfusion for the assessment of the response to the initial fluid bolus of 30 mL/kg. MAP, mean arterial pressure; S_cvO₂, central venous O₂ saturation; P_cv-aCO₂, central venous–arterial PCO₂ difference; CRT, capillary-refill time; CVP, central venous pressure