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. 2020 Apr 15;15:81. doi: 10.1186/s11671-020-03309-w

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a In vivo ultrasound imaging of tumors, livers, and subcutaneous areas at different time after injection of Fe₃O₄/Na₂CO₃@PLGA/Cy5.5/cRGD NPs. b Echo intensity rate as a function of time is calculated by tissue/blank, tissue represents the echo intensity of the tumor, liver, or subcutaneous area, blank represents the echo intensity before injection