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. 2019 Dec 10;18:214. doi: 10.1186/s12944-019-1164-7

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Measurement of BDNF (pg/ml) secretion by RIN5F cells in vitro. a) Effect of various PUFAs on the secretion of BDNF (pg/ml) by RIN5F cells in vitro that was suppressed by AL/BP. b) Effect of various PUFAs on the secretion of BDNF (pg/ml) by RIN5F cells in vitro that was suppressed by STZ (20 mM)/DB (100 ng/ml). All values expressed as mean ± SEM. *P < 0.01 vs untreated control § P < 0.001 vs toxin -treated group. AA, arachidonic acid; GLA, γ-linolenic acid; EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid. c) Effect of LXA4 (10, 25, 50 and 100 ng/ml) at the end of 12, 24 and 48 h of supplementations on BDNF secretion by RIN5F cells in vitro. All values expressed as mean ± SEM. *P < 0.001 vs respective untreated control