Fig 6.

Relative expression of TGF-β/Smad signaling pathway key genes TGF-β1 (a), Smad3 (b), TGF-βRI (c), Smad4 (d), TGF-βRII (e), Smad7 (f), PU.1 (g), and IRF-4 (h) in goat PBMCs during different stages of H. contortus infection. P-800: Goats (n = 5 each) infected with 800 H. contortus L3; P-2400: Goats infected with 2400 H. contortus L3; P-8000 Goats infected with 8000 H. contortus L3; 0–35: Days post-infection. The control group was kept untreated. The significant level was set at *p < 0.05, **p < 0.01, ***p < 0.001, and ns non-significant compared with the untreated group (control). Data are representative of three independent experiments.