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. 2013 Jun 7;381(9882):1987–2015. doi: 10.1016/S0140-6736(13)61097-1

Table 2.

Deaths (in thousands) and age-standardised death rates per 100 000 for 231 causes in 1990 and 2010 for all ages, both sexes combined, and percentage change from 1990 to 2010 in China

All ages deaths (thousands)
Age-standardised death rate (per 100 000)
1990 2010 Median %Δ 1990 2010 Median %Δ
All causes 7997·5 (7663·4–8426·7) 8303·7 (7939·6–8678·7) 4·0 895·9 (858·8–943·6) 606·8 (580·7–632·7) –32·1
Communicable, maternal, neonatal, and nutritional disorders 1207·8 (1105·1–1303·8) 490·4 (441·9–548·5) –59·5 108·5 (100·3–117·4) 40·7 (36·6–45·2) –62·5
HIV/AIDS and tuberculosis 169·2 (140·8–200·2) 80·9 (63·6–100·1) −52·2 18·6 (15·4–22·0) 5·5 (4·3–6·8) −70·2
Tuberculosis 169·0 (140·5–200·0) 44·7 (32·7–54·2) −73·0 18·5 (15·4–21·9) 3·1 (2·3–3·8) −82·8
HIV/AIDS 0·2 (0·0–0·6) 36·2 (25·1–49·2) 13 860·7 <0·05 (0·0–0·1) 2·4 (1·7–3·3) 9447·6
HIV disease resulting in mycobacterial infection <0·05 (0·0–0·1) 2·0 (1·4–2·7) 6050·5 <0·05 (0·0–0·05) 0·1 (0·1–0·2) 4159·1
HIV disease resulting in other specified or unspecified diseases 0·2 (0·0–0·5) 34·2 (23·9–46·7) 14 809·7 <0·05 (0·0–0·1) 2·3 (1·6–3·1) 10 224·8
Diarrhoea, lower respiratory infections, meningitis, and other common infectious diseases 558·4 (492·7–623·3) 223·2 (188·9–257·3) −59·9 50·6 (45·6–56·5) 18·2 (15·5–21·1) −63·9
Diarrhoeal diseases 71·3 (61·5–83·2) 4·4 (3·7–5·3) −93·9 6·4 (5·6–7·3) 0·4 (0·3–0·5) −94·0
Cholera 2·0 (1·2–3·5) 0·1 (0·1–0·2) −95·3 0·2 (0·1–0·3) <0·05 (0·0–0·05) −94·0
Other salmonella infections 5·6 (4·0–7·9) 0·4 (0·3–0·5) −93·6 0·5 (0·4–0·7) <0·05 (0·0–0·05) −93·8
Shigellosis 4·8 (3·6–6·5) 0·3 (0·3–0·5) −93·1 0·5 (0·4–0·6) <0·05 (0·0–0·05) −93·9
Enteropathogenic E coli infection 6·6 (4·0–10·2) 0·3 (0·2–0·5) −95·4 0·5 (0·3–0·8) <0·05 (0·0–0·1) −94·1
Enterotoxigenic E coli infection 6·4 (4·8–8·4) 0·5 (0·3–0·6) −92·9 0·6 (0·5–0·8) <0·05 (0·0–0·1) −93·9
Campylobacter enteritis 6·7 (4·3–9·8) 0·4 (0·3–0·6) −94·4 0·6 (0·4–0·8) <0·05 (0·0–0·1) −94·0
Amoebiasis 1·8 (1·3–2·5) 0·2 (0·1–0·2) −91·4 0·2 (0·1–0·3) <0·05 (0·0–0·05) −93·9
Cryptosporidiosis 5·5 (3·4–8·4) 0·3 (0·2–0·4) −95·4 0·4 (0·3–0·7) <0·05 (0·0–0·05) −94·0
Rotaviral enteritis 17·8 (13·1–23·6) 0·9 (0·6–1·2) −94·9 1·5 (1·1–1·9) 0·1 (0·1–0·1) −94·0
Other diarrhoeal diseases 14·1 (9·6–20·0) 1·1 (0·8–1·5) −92·2 1·4 (1·0–2·0) 0·1 (0·1–0·1) −93·9
Typhoid and paratyphoid fevers 12·0 (1·4–22·6) 11·9 (1·4–21·9) −1·0 1·0 (0·1–1·9) 0·9 (0·1–1·7) −6·5
Lower respiratory infections 392·4 (342·3–441·9) 195·2 (162·9–226·3) −50·1 36·4 (32·3–41·5) 15·9 (13·4–18·5) −56·2
Influenza 75·2 (61·9–91·1) 40·8 (33·4–47·9) −45·5 7·1 (6·0–8·6) 3·3 (2·7–3·9) −53·7
Pneumococcal pneumonia 89·7 (74·8–107·1) 60·5 (48·9–72·4) −32·3 9·0 (7·6–10·9) 4·8 (3·9–5·8) −46·3
H influenzae type B pneumonia 102·2 (79·6–126·8) 30·4 (25·5–35·8) −70·3 8·6 (6·8–10·5) 2·6 (2·2–3·1) −69·9
Respiratory syncytial virus pneumonia 56·1 (39·4–74·7) 7·3 (5·5–10·0) −87·2 4·3 (3·1–5·7) 0·8 (0·5–1·1) −83·0
Other lower respiratory infections 69·2 (53·4–93·3) 56·2 (43·0–70·0) −17·5 7·3 (5·7–9·6) 4·5 (3·4–5·6) −38·2
Upper respiratory infections 0·3 (0·3–0·4) <0·05 (0·0–0·1) −89·4 <0·05 (0·0–0·05) <0·05 (0·0–0·05) −84·9
Otitis media 1·0 (0·0–11·6) 0·3 (0·0–2·9) −74·6 0·1 (0·0–1·0) <0·05 (0·0–0·3) −74·1
Meningitis 30·6 (24·5–34·7) 7·7 (6·4–10·2) −76·0 2·7 (2·2–3·1) 0·6 (0·5–0·8) −78·3
Pneumococcal meningitis 5·8 (4·3–6·9) 1·4 (1·1–2·0) −77·0 0·5 (0·4–0·6) 0·1 (0·1–0·2) −79·5
H influenzae type B meningitis 4·8 (3·8–5·9) 0·9 (0·7–1·2) −81·1 0·4 (0·3–0·5) 0·1 (0·1–0·1) −78·5
Meningococcal infection 4·1 (3·0–4·9) 1·0 (0·8–1·3) −77·7 0·4 (0·3–0·4) 0·1 (0·1–0·1) −79·6
Other meningitis 15·9 (12·1–18·4) 4·4 (3·6–6·0) −74·1 1·5 (1·1–1·7) 0·3 (0·3–0·5) −78·1
Encephalitis 3·7 (3·0–4·4) 0·7 (0·5–0·8) −82·1 0·3 (0·2–0·3) 0·1 (0·1–0·1) −78·7
Diphtheria 0·2 (0·0–1·4) <0·05 (0·0–0·4) −73·4 <0·05 (0·0–0·1) <0·05 (0·0–0·05) −68·8
Whooping cough 3·3 (0·0–16·4) 0·5 (0·0–2·2) −86·0 0·3 (0·0–1·3) <0·05 (0·0–0·2) −80·6
Tetanus 19·0 (8·9–34·8) 1·7 (0·5–5·2) −91·9 1·6 (0·7–3·1) 0·1 (0·0–0·4) −91·3
Measles 23·7 (7·9–60·2) 0·4 (0·1–1·1) −98·3 1·8 (0·6–4·6) <0·05 (0·0–0·1) −97·7
Varicella 0·8 (0·0–5·5) 0·5 (0·0–3·7) −34·0 0·1 (0·0–0·5) <0·05 (0·0–0·3) −42·6
Neglected tropical diseases and malaria 24·0 (10·9–65·7) 14·9 (4·7–57·6) −45·7 2·4 (1·0–7·0) 1·1 (0·3–4·0) −58·5
Malaria 0·2 (0·1–0·3) 0·1 (0·0–0·1) −63·2 <0·05 (0·0–0·05) <0·05 (0·0–0·05) −72·1
Leishmaniasis 6·5 (2·8–14·7) 1·8 (0·8–3·6) −71·2 0·6 (0·2–1·2) 0·1 (0·1–0·3) −73·5
Schistosomiasis 8·5 (0·0–50·4) 8·5 (0·0–50·2) 0·2 0·9 (0·0–5·6) 0·6 (0·0–3·5) −37·9
Cysticercosis <0·05 (0·0–0·1) <0·05 (0·0–0·2) 54·0 <0·05 (0·0–0·05) <0·05 (0·0–0·05) 3·8
Echinococcosis 0·6 (0·0–2·3) 0·4 (0·0–1·6) −31·5 0·1 (0·0–0·2) <0·05 (0·0–0·1) −56·1
Dengue 1·0 (0·2–3·2) 1·0 (0·4–2·3) 11·6 0·1 (0·0–0·3) 0·1 (0·0–0·2) −5·6
Rabies 2·0 (1·2–3·2) 1·2 (0·4–2·2) −52·6 0·2 (0·1–0·3) 0·1 (0·0–0·2) −66·1
Intestinal nematode infections 1·4 (0·0–6·7) 0·3 (0·0–1·7) −75·3 0·1 (0·0–0·5) <0·05 (0·0–0·2) −69·9
Ascariasis 1·4 (0·0–6·7) 0·3 (0·0–1·7) −75·3 0·1 (0·0–0·5) <0·05 (0·0–0·2) −69·9
Other neglected tropical diseases 3·9 (1·8–5·3) 1·5 (0·6–4·1) −73·0 0·4 (0·2–0·5) 0·1 (0·0–0·3) −81·1
Maternal disorders 20·6 (15·9–28·5) 5·0 (3·6–6·3) −75·7 1·6 (1·3–2·2) 0·3 (0·2–0·4) −78·2
Maternal haemorrhage 5·6 (4·4–7·7) 1·6 (1·2–2·1) −70·5 0·4 (0·3–0·6) 0·1 (0·1–0·1) −74·4
Maternal sepsis 3·0 (2·3–4·1) 0·7 (0·5–0·9) −75·4 0·2 (0·2–0·3) 0·1 (0·0–0·1) −77·2
Hypertensive disorders of pregnancy 2·4 (1·9–3·3) 0·5 (0·4–0·6) −79·0 0·2 (0·1–0·3) <0·05 (0·0–0·05) −80·7
Obstructed labour 0·2 (0·2–0·3) <0·05 (0·0–0·1) −74·5 <0·05 (0·0–0·05) <0·05 (0·0–0·05) −77·5
Abortion 3·4 (2·6–4·7) 0·8 (0·6–1·1) −75·0 0·3 (0·2–0·4) 0·1 (0·0–0·1) −77·4
Other maternal disorders 6·0 (4·7–8·3) 1·2 (0·9–1·5) −79·6 0·5 (0·4–0·7) 0·1 (0·1–0·1) −81·8
Neonatal disorders 343·0 (291·9–394·9) 83·4 (61·2–102·7) −75·7 26·4 (22·5–30·4) 9·4 (6·9–11·6) −64·5
Preterm birth complications 97·4 (69·2–131·7) 27·6 (20·0–37·3) −71·6 7·5 (5·3–10·2) 3·1 (2·3–4·2) −58·4
Neonatal encephalopathy (birth asphyxia/birth trauma) 109·7 (75·2–150·6) 26·8 (16·4–39·8) −75·4 8·5 (5·8–11·6) 3·0 (1·9–4·5) −64·0
Sepsis and other infectious disorders of the newborn baby 5·1 (1·9–11·2) 1·6 (0·8–3·2) −65·9 0·4 (0·1–0·9) 0·2 (0·1–0·4) −50·0
Other neonatal disorders 130·9 (77·9–186·4) 27·4 (18·0–40·1) −79·2 10·1 (6·0–14·4) 3·1 (2·0–4·5) −69·6
Nutritional deficiencies 20·0 (16·8–31·9) 13·4 (6·8–17·4) −25·2 2·0 (1·7–3·1) 1·1 (0·5–1·4) −40·2
Protein-energy malnutrition 14·8 (12·2–20·4) 9·2 (5·2–12·0) −36·0 1·5 (1·2–2·0) 0·7 (0·4–1·0) −47·5
Iodine deficiency 0·2 (0·2–0·2) 0·2 (0·1–0·3) 36·2 <0·05 (0·0–0·05) <0·05 (0·0–0·05) 12·8
Iron-deficiency anaemia 3·9 (3·3–4·9) 2·8 (1·6–3·5) −28·0 0·4 (0·3–0·5) 0·2 (0·1–0·3) −44·9
Other nutritional deficiencies 1·1 (1·0–1·5) 1·2 (0·7–1·6) 9·5 0·1 (0·1–0·2) 0·1 (0·1–0·1) −20·6
Other communicable, maternal, neonatal, and nutritional disorders 72·6 (63·1–82·5) 69·7 (57·7–78·6) −4·0 7·0 (6·1–7·8) 5·1 (4·1–5·7) −27·6
Sexually transmitted diseases excluding HIV 19·2 (11·2–27·8) 2·7 (1·7–4·3) −86·8 1·7 (0·9–2·5) 0·3 (0·2–0·4) −85·0
Syphilis 17·0 (10·7–25·2) 2·2 (1·3–3·7) −87·2 1·4 (0·9–2·1) 0·2 (0·1–0·4) −84·7
Sexually transmitted chlamydial diseases 0·5 (0·2–0·9) 0·1 (0·1–0·2) −84·1 0·1 (0·0–0·1) <0·05 (0·0–0·05) −89·3
Gonococcal infection 0·4 (0·1–0·7) 0·1 (0·1–0·1) −84·0 <0·05 (0·0–0·1) <0·05 (0·0–0·05) −89·3
Other sexually transmitted diseases 1·3 (0·4–2·2) 0·3 (0·2–0·5) −84·0 0·1 (0·0–0·2) <0·05 (0·0–0·05) −89·3
Hepatitis 33·3 (30·1–36·7) 43·8 (37·7–50·7) 30·9 3·4 (3·1–3·8) 3·0 (2·5–3·4) −13·5
Acute hepatitis A 7·0 (3·1–16·9) 5·2 (1·8–17·7) −29·4 0·7 (0·3–1·7) 0·4 (0·1–1·2) −53·6
Acute hepatitis B 21·3 (16·6–27·9) 35·1 (23·5–44·1) 67·8 2·3 (1·8–3·0) 2·3 (1·6–3·0) 7·0
Acute hepatitis C 0·7 (0·4–1·1) 1·2 (0·8–1·6) 88·2 0·1 (0·0–0·1) 0·1 (0·1–0·1) 16·0
Acute hepatitis E 4·2 (2·3–7·1) 2·3 (1·1–4·1) −47·3 0·3 (0·2–0·6) 0·2 (0·1–0·3) −52·0
Other infectious diseases 20·1 (16·6–27·2) 23·2 (13·0–28·5) 22·9 1·9 (1·6–2·5) 1·8 (1·0–2·3) 2·5
Non-communicable diseases 5937·8 (5679·4–6331·6) 7017·1 (6663·3–7310·2) 18·7 708·5 (678·0–754·9) 509·4 (483·6–530·3) –27·8
Neoplasms 1503·6 (1362·6–1710·4) 2133·5 (1905·4–2314·6) 43·1 170·0 (154·5–193·7) 148·0 (131·9–160·4) −12·0
Oesophageal cancer 168·8 (138·0–225·8) 176·0 (117·9–224·7) 10·1 19·8 (16·1–26·3) 12·3 (8·2–15·8) −34·4
Stomach cancer 297·4 (228·5–403·4) 297·0 (209·5–385·3) 0·0 34·3 (26·3–46·6) 20·8 (14·7–27·0) −39·2
Liver cancer 238·6 (199·6–283·9) 369·7 (322·0–467·0) 54·0 26·5 (22·3–31·7) 25·0 (21·6–31·4) −6·4
Liver cancer secondary to hepatitis B 128·5 (107·6–153·3) 200·8 (170·0–253·6) 55·4 14·3 (12·0–17·0) 13·5 (11·4–16·9) −5·6
Liver cancer secondary to hepatitis C 42·5 (36·1–51·8) 71·8 (60·0–89·4) 69·8 4·9 (4·2–6·0) 4·9 (4·1–6·1) 1·5
Liver cancer secondary to alcohol use 44·4 (36·2–53·5) 67·5 (56·2–87·6) 51·4 4·9 (4·0–5·9) 4·5 (3·8–5·8) −8·2
Other liver cancer 23·3 (19·1–28·5) 29·5 (24·3–39·3) 25·1 2·4 (2·0–2·9) 1·9 (1·6–2·6) −21·2
Larynx cancer 9·8 (4·4–18·8) 13·5 (5·6–25·3) 34·8 1·1 (0·5–2·2) 0·9 (0·4–1·8) −19·3
Trachea, bronchus, and lung cancers 260·2 (216·2–372·9) 513·3 (353·4–598·5) 109·5 30·0 (25·0–43·2) 35·8 (24·5–41·8) 27·2
Breast cancer 29·2 (27·9–30·5) 52·5 (47·4–59·6) 78·4 3·3 (3·1–3·4) 3·5 (3·1–3·9) 5·0
Cervical cancer 20·7 (13·2–30·7) 25·4 (12·4–32·5) 31·3 2·4 (1·5–3·5) 1·7 (0·8–2·2) −24·5
Uterine cancer 5·4 (3·7–11·8) 10·5 (3·7–13·8) 139·3 0·6 (0·4–1·3) 0·7 (0·3–0·9) 42·8
Prostate cancer 3·9 (2·4–7·0) 11·3 (4·7–17·6) 138·2 0·5 (0·3–0·9) 0·9 (0·4–1·3) 43·7
Colon and rectum cancers 93·0 (76·9–105·2) 150·4 (130·5–186·1) 59·4 10·7 (8·9–12·1) 10·6 (9·1–13·0) −2·3
Mouth cancer 7·5 (6·2–8·5) 14·0 (10·3–18·4) 87·1 0·9 (0·7–1·0) 1·0 (0·7–1·3) 12·6
Nasopharynx cancer 22·1 (15·2–32·4) 34·4 (21·1–48·9) 49·5 2·4 (1·7–3·6) 2·3 (1·4–3·2) −9·1
Cancer of other part of pharynx and oropharynx 4·1 (2·5–5·5) 5·1 (3·6–8·3) 20·9 0·5 (0·3–0·6) 0·3 (0·2–0·6) −26·1
Gallbladder and biliary tract cancer 17·8 (12·7–27·3) 29·8 (19·5–40·5) 67·6 2·1 (1·5–3·2) 2·1 (1·4–2·9) 1·7
Pancreatic cancer 32·1 (24·9–43·1) 58·2 (43·2–74·8) 82·9 3·7 (2·9–5·0) 4·0 (3·0–5·2) 9·4
Malignant melanoma of skin 2·7 (1·4–3·4) 6·7 (4·5–11·4) 131·5 0·3 (0·2–0·4) 0·5 (0·3–0·8) 45·8
Non-melanoma skin cancer 3·2 (1·5–5·8) 4·5 (2·4–8·1) 41·1 0·4 (0·2–0·7) 0·3 (0·2–0·6) −15·7
Ovarian cancer 14·4 (9·8–18·4) 20·7 (13·6–29·1) 34·4 1·6 (1·1–2·0) 1·4 (0·9–1·9) −18·7
Testicular cancer 1·0 (0·5–1·4) 0·8 (0·4–1·5) −18·3 0·1 (0·0–0·1) 0·1 (0·0–0·1) −43·5
Kidney and other urinary organ cancers 13·7 (9·9–19·5) 32·0 (22·5–41·4) 134·9 1·5 (1·1–2·2) 2·2 (1·6–2·9) 47·2
Bladder cancer 14·5 (12·3–18·6) 22·9 (17·6–28·2) 59·2 1·8 (1·5–2·2) 1·7 (1·3–2·1) −4·2
Brain and nervous system cancers 35·5 (23·1–48·4) 48·9 (29·3–67·1) 38·0 3·8 (2·5–5·2) 3·3 (2·0–4·6) −11·5
Thyroid cancer 4·8 (3·7–6·5) 8·1 (5·7–10·6) 69·5 0·5 (0·4–0·7) 0·6 (0·4–0·7) 4·9
Hodgkin's disease 1·5 (1·0–2·2) 1·2 (0·7–1·7) −20·2 0·1 (0·1–0·2) 0·1 (0·1–0·1) −43·0
Non-Hodgkin lymphoma 21·0 (17·8–24·3) 27·7 (22·6–33·7) 30·3 2·2 (1·9–2·6) 2·0 (1·6–2·4) −13·9
Multiple myeloma 5·1 (3·5–7·8) 9·4 (5·4–13·3) 90·2 0·5 (0·4–0·8) 0·7 (0·4–0·9) 21·4
Leukaemia 53·0 (42·3–67·5) 58·0 (44·2–69·2) 13·7 4·9 (3·9–6·2) 4·2 (3·2–5·0) −10·5
Other neoplasms 122·5 (84·9–149·0) 131·6 (95·7–171·3) 6·3 13·4 (9·3–16·4) 9·2 (6·7–11·9) −32·1
Cardiovascular and circulatory diseases 2167·5 (2054·9–2462·4) 3136·2 (2827·1–3274·6) 47·4 267·7 (253·5–304·4) 230·8 (207·4–241·1) −12·2
Rheumatic heart disease 131·4 (120·1–147·3) 57·1 (49·8–63·0) −56·4 14·9 (13·7–16·8) 4·0 (3·5–4·5) −72·7
Ischaemic heart disease 450·3 (409·2–594·5) 948·7 (774·5–1024·6) 120·3 55·7 (50·6–73·9) 70·1 (57·2–76·0) 31·6
Cerebrovascular disease 1340·6 (1237·6–1623·2) 1726·7 (1463·2–1848·6) 34·5 167·0 (154·5–201·6) 126·9 (107·9–135·8) −20·8
Ischaemic stroke 426·4 (304·4–639·7) 609·6 (478·3–808·4) 44·7 56·3 (40·8–83·3) 46·7 (36·7–61·6) −16·2
Haemorrhagic and other non-ischemic stroke 914·2 (657·9–1146·4) 1117·2 (887·1–1359·1) 22·1 110·7 (79·1–139·5) 80·2 (63·8–97·9) −27·7
Hypertensive heart disease 133·7 (106·7–174·0) 172·9 (136·4–210·6) 31·5 16·9 (13·4–21·8) 12·8 (10·1–15·7) −22·8
Cardiomyopathy and myocarditis 32·6 (20·4–48·1) 35·2 (24·5–49·5) 8·8 3·6 (2·3–5·1) 2·5 (1·8–3·6) −28·5
Atrial fibrillation and flutter 4·8 (1·9–10·3) 12·9 (5·6–26·6) 175·1 0·6 (0·2–1·5) 1·0 (0·4–2·1) 58·7
Aortic aneurysm 36·3 (12·9–62·6) 58·2 (30·7–90·3) 61·4 4·5 (1·6–7·8) 4·3 (2·2–6·6) −3·9
Peripheral vascular disease 3·3 (1·2–6·6) 9·1 (4·1–17·2) 180·4 0·4 (0·1–0·9) 0·7 (0·3–1·3) 63·7
Endocarditis 9·5 (6·8–12·8) 12·4 (9·8–15·8) 31·6 1·0 (0·7–1·3) 0·9 (0·7–1·1) −8·4
Other cardiovascular and circulatory diseases 25·0 (20·1–31·1) 103·0 (94·5–112·6) 318·5 3·1 (2·5–3·9) 7·5 (6·9–8·3) 148·6
Chronic respiratory diseases 1496·5 (1444·7–1550·5) 1022·9 (965·4–1089·3) −31·8 189·0 (182·1–196·2) 77·2 (72·8–82·3) −59·3
Chronic obstructive pulmonary disease 1426·9 (1340·1–1509·5) 934·4 (846·6–1032·3) −34·3 180·7 (169·9–190·9) 70·6 (64·0–78·1) −60·8
Pneumoconiosis 6·1 (3·6–10·6) 4·1 (1·9–7·2) −32·7 0·7 (0·4–1·3) 0·3 (0·1–0·5) −59·1
Asthma 25·2 (16·9–34·8) 19·9 (16·6–27·3) −22·2 3·1 (2·1–4·3) 1·5 (1·2–2·0) −52·7
Interstitial lung disease and pulmonary sarcoidosis 5·0 (2·8–8·0) 8·6 (4·8–12·9) 73·6 0·6 (0·3–0·9) 0·6 (0·3–0·9) 6·9
Other chronic respiratory diseases 33·4 (25·8–43·2) 55·9 (33·6–69·0) 72·4 4·0 (3·0–5·2) 4·2 (2·6–5·2) 9·2
Cirrhosis of the liver 174·9 (127·0–198·9) 114·4 (90·0–187·8) −45·7 19·6 (14·2–22·3) 7·7 (6·1–12·7) −67·3
Cirrhosis of the liver secondary to hepatitis B 78·7 (55·0–93·1) 52·3 (39·3–86·5) −44·1 9·0 (6·2–10·6) 3·5 (2·7–5·9) −66·7
Cirrhosis of the liver secondary to hepatitis C 37·9 (25·9–44·5) 24·5 (18·8–40·7) −45·2 4·4 (3·0–5·2) 1·7 (1·3–2·8) −67·5
Cirrhosis of the liver secondary to alcohol use 35·9 (24·2–43·7) 25·3 (18·8–42·9) −41·0 4·0 (2·7–4·9) 1·7 (1·3–2·9) −64·5
Other cirrhosis of the liver 22·4 (15·5–26·9) 12·3 (9·0–20·8) −54·2 2·3 (1·6–2·8) 0·8 (0·6–1·4) −70·5
Digestive diseases (except cirrhosis) 163·4 (142·8–181·2) 133·0 (116·8–153·1) −19·0 19·1 (16·7–21·2) 9·7 (8·5–11·2) −49·4
Peptic ulcer disease 54·9 (41·4–61·0) 19·3 (16·5–23·2) −65·4 6·5 (4·9–7·3) 1·4 (1·2–1·7) −78·9
Gastritis and duodenitis 2·5 (1·2–5·7) 1·3 (0·8–2·7) −43·8 0·3 (0·1–0·7) 0·1 (0·1–0·2) −64·1
Appendicitis 5·6 (3·3–7·7) 1·4 (0·9–2·5) −76·7 0·6 (0·4–0·8) 0·1 (0·1–0·2) −84·2
Paralytic ileus and intestinal obstruction without hernia 17·3 (9·7–21·7) 11·2 (7·8–18·9) −44·6 1·9 (1·1–2·3) 0·8 (0·6–1·4) −62·0
Inguinal or femoral hernia 2·0 (1·9–2·0) 1·1 (1·0–1·1) −43·4 0·2 (0·2–0·2) 0·1 (0·1–0·1) −65·9
Non-infective inflammatory bowel disease 2·8 (1·0–4·9) 2·4 (1·2–3·9) −10·0 0·3 (0·1–0·5) 0·2 (0·1–0·3) −38·9
Vascular disorders of intestine 6·0 (1·8–17·6) 10·3 (3·8–26·5) 86·0 0·7 (0·2–2·2) 0·8 (0·3–2·0) 11·6
Gall bladder and bile duct disease 15·5 (11·3–21·1) 18·2 (11·5–27·1) 16·5 1·8 (1·3–2·5) 1·3 (0·8–2·0) −26·4
Pancreatitis 6·2 (3·2–9·6) 8·3 (5·2–11·5) 34·7 0·7 (0·4–1·1) 0·6 (0·4–0·8) −18·0
Other digestive diseases 50·7 (33·2–63·2) 59·5 (45·7–91·5) 11·1 6·0 (3·9–7·5) 4·3 (3·3–6·6) −31·1
Neurological disorders 58·5 (46·1–74·8) 80·6 (65·1–112·4) 34·5 6·5 (5·1–8·3) 6·1 (4·9–8·5) −8·9
Alzheimer's disease and other dementias 25·8 (17·0–35·8) 50·0 (36·8–77·6) 87·9 3·4 (2·2–4·8) 3·9 (2·8–6·1) 13·0
Parkinson's disease 4·1 (2·4–5·9) 7·3 (4·7–11·3) 73·6 0·5 (0·3–0·7) 0·5 (0·3–0·8) 9·5
Epilepsy 18·7 (12·0–23·0) 12·2 (10·4–17·8) −37·3 1·7 (1·1–2·0) 0·9 (0·7–1·3) −50·1
Multiple sclerosis 3·2 (1·3–5·3) 1·6 (1·0–2·6) −54·2 0·3 (0·1–0·6) 0·1 (0·1–0·2) −71·8
Other neurological disorders 6·6 (3·6–17·1) 9·5 (5·3–18·8) 53·9 0·7 (0·4–1·6) 0·7 (0·4–1·4) 12·6
Mental and behavioural disorders 23·3 (15·0–30·0) 20·7 (16·7–29·8) −16·9 2·4 (1·6–3·1) 1·4 (1·1–2·1) −44·4
Schizophrenia 12·6 (8·3–16·0) 8·9 (7·1–14·1) −33·4 1·3 (0·9–1·7) 0·6 (0·5–1·0) −57·7
Alcohol use disorders 3·3 (1·7–7·1) 4·6 (2·3–8·2) 44·6 0·3 (0·2–0·7) 0·3 (0·2–0·5) −7·8
Drug use disorders 3·2 (0·5–6·6) 4·8 (3·2–10·5) 41·3 0·3 (0·1–0·6) 0·3 (0·2–0·8) 12·8
Opioid use disorders 1·0 (0·2–2·0) 1·5 (1·0–3·4) 45·1 0·1 (0·0–0·2) 0·1 (0·1–0·3) 15·6
Cocaine use disorders 0·1 (0·0–0·3) <0·05 (0·0–0·05) −96·7 <0·05 (0·0–0·05) <0·05 (0·0–0·05) −97·4
Amphetamine use disorders 0·1 (0·0–0·1) <0·05 (0·0–0·05) −93·4 <0·05 (0·0–0·05) <0·05 (0·0–0·05) −94·7
Other drug use disorders 2·0 (0·3–4·1) 3·2 (2·1–6·7) 53·5 0·2 (0·0–0·4) 0·2 (0·2–0·5) 22·3
Eating disorders 1·5 (0·4–2·6) 0·7 (0·5–1·4) −69·1 0·1 (0·0–0·3) 0·1 (0·0–0·1) −76·9
Other mental and behavioural disorders 2·7 (0·8–4·7) 1·6 (1·0–3·2) −63·4 0·3 (0·1–0·5) 0·1 (0·1–0·2) −74·8
Diabetes, urogenital, blood, and endocrine diseases 186·2 (158·2–245·1) 294·9 (252·1–323·1) 65·3 20·6 (17·6–27·3) 21·3 (18·2–23·3) 7·9
Diabetes mellitus 70·5 (64·2–102·4) 160·1 (123·7–176·2) 141·6 8·0 (7·3–11·8) 11·5 (8·8–12·7) 52·3
Acute glomerulonephritis 16·2 (1·7–61·4) 3·0 (1·1–6·4) −72·0 1·7 (0·2–6·5) 0·2 (0·1–0·5) −80·5
Chronic kidney diseases 53·9 (47·6–75·5) 82·0 (66·6–93·1) 62·0 6·0 (5·3–8·4) 5·8 (4·7–6·6) 2·5
Chronic kidney disease due to diabetes mellitus 8·8 (7·2–12·6) 14·5 (11·5–17·4) 75·9 1·0 (0·8–1·5) 1·0 (0·8–1·2) 5·7
Chronic kidney disease due to hypertension 10·5 (9·0–14·9) 16·6 (13·3–19·2) 66·8 1·2 (1·0–1·7) 1·2 (0·9–1·4) 3·4
Chronic kidney disease unspecified 34·6 (30·0–48·5) 51·0 (41·3–58·7) 57·1 3·8 (3·3–5·3) 3·6 (2·9–4·2) 1·5
Urinary diseases and male infertility 14·8 (7·9–20·1) 13·0 (9·8–20·1) −19·4 1·7 (0·9–2·3) 1·0 (0·7–1·5) −47·8
Tubulointerstitial nephritis, pyelonephritis, and urinary tract infections 7·8 (4·5–11·0) 8·5 (6·4–12·7) 7·7 0·9 (0·5–1·2) 0·6 (0·5–0·9) −27·7
Urolithiasis 5·6 (2·3–12·5) 3·0 (0·9–7·8) −46·9 0·7 (0·3–1·5) 0·2 (0·1–0·6) −67·3
Other urinary diseases 1·5 (0·8–2·0) 1·5 (1·1–2·5) −3·7 0·2 (0·1–0·2) 0·1 (0·1–0·2) −40·0
Gynaecological diseases 2·7 (2·0–3·7) 1·7 (1·3–2·2) −38·3 0·3 (0·2–0·4) 0·1 (0·1–0·2) −58·3
Uterine fibroids <0·05 (0·0–0·05) <0·05 (0·0–0·05) −76·8 <0·05 (0·0–0·05) <0·05 (0·0–0·05) −75·2
Endometriosis 0·0 (0·0–0·0) 0·0 (0·0–0·0) 0·0 0·0 (0·0–0·0) 0·0 (0·0–0·0) 0·0
Genital prolapse 0·1 (0·0–0·1) <0·05 (0·0–0·05) −36·1 <0·05 (0·0–0·05) <0·05 (0·0–0·05) −58·9
Other gynaecological diseases 2·6 (1·9–3·7) 1·6 (1·3–2·2) −38·2 0·3 (0·2–0·4) 0·1 (0·1–0·1) −58·1
Haemoglobinopathies and haemolytic anaemias 20·5 (8·1–39·0) 15·2 (8·5–24·5) −23·6 2·1 (0·8–4·0) 1·2 (0·6–1·8) −43·8
Thalassaemias 7·5 (4·3–13·5) 3·7 (2·7–4·8) −49·3 0·6 (0·4–1·1) 0·3 (0·2–0·4) −54·8
Sickle cell disorders 0·1 (0·0–0·1) <0·05 (0·0–0·05) −43·4 <0·05 (0·0–0·05) <0·05 (0·0–0·05) −53·2
G6PD deficiency 0·8 (0·5–1·5) 0·6 (0·5–0·8) −21·9 0·1 (0·1–0·1) <0·05 (0·0–0·1) −42·3
Other haemoglobinopathies and haemolytic anaemias 12·1 (4·3–25·2) 10·8 (4·5–20·1) −4·3 1·4 (0·5–2·9) 0·8 (0·3–1·6) −36·6
Other endocrine, nutritional, blood, and immune disorders 7·5 (4·7–13·3) 20·0 (10·7–30·7) 176·8 0·7 (0·5–1·4) 1·5 (0·8–2·3) 119·2
Musculoskeletal disorders 17·3 (9·7–22·4) 26·2 (19·3–40·7) 41·2 2·0 (1·1–2·5) 1·9 (1·4–2·9) −11·2
Rheumatoid arthritis 8·9 (5·2–11·8) 11·3 (7·9–16·6) 22·9 1·1 (0·6–1·4) 0·8 (0·6–1·2) −24·2
Other musculoskeletal disorders 8·3 (3·6–12·0) 14·9 (11·6–25·1) 55·3 0·9 (0·4–1·3) 1·1 (0·8–1·8) 2·5
Other non-communicable diseases 146·6 (122·3–195·6) 54·8 (42·8–73·6) −62·8 11·6 (9·7–15·4) 5·4 (4·1–7·4) −54·0
Congenital anomalies 130·1 (106·0–176·9) 45·7 (33·5–65·1) −65·0 10·0 (8·2–13·6) 4·6 (3·4–6·7) −53·9
Neural tube defects 25·0 (11·6–43·5) 3·2 (1·7–6·6) −87·5 1·9 (0·9–3·4) 0·3 (0·2–0·7) −82·7
Congenital heart anomalies 73·4 (63·2–86·0) 31·3 (24·6–40·4) −57·5 5·6 (4·9–6·6) 3·2 (2·5–4·1) −44·1
Cleft lip and cleft palate 4·3 (1·1–11·9) 0·7 (0·3–1·5) −81·1 0·3 (0·1–0·9) 0·1 (0·0–0·2) −72·4
Down's syndrome 2·1 (0·9–4·3) 0·9 (0·6–1·3) −56·4 0·2 (0·1–0·3) 0·1 (0·1–0·1) −50·1
Other chromosomal abnormalities 11·4 (2·6–35·8) 2·9 (1·3–6·9) −69·5 0·9 (0·2–2·8) 0·3 (0·1–0·8) −58·6
Other congenital anomalies 14·0 (3·4–32·5) 6·8 (4·1–13·6) −43·5 1·1 (0·3–2·5) 0·7 (0·4–1·4) −28·4
Skin and subcutaneous diseases 12·7 (9·0–15·3) 7·4 (5·5–9·0) −41·7 1·3 (1·0–1·6) 0·6 (0·4–0·7) −57·0
Cellulitis 3·4 (2·4–4·2) 1·6 (1·3–1·9) −53·1 0·3 (0·2–0·4) 0·1 (0·1–0·1) −64·6
Abscess, impetigo, and other bacterial skin diseases 5·5 (3·6–6·9) 2·3 (1·8–2·7) −58·4 0·5 (0·4–0·6) 0·2 (0·1–0·2) −66·6
Decubitus ulcer 3·7 (2·9–4·7) 3·5 (2·4–4·5) −7·7 0·5 (0·4–0·6) 0·3 (0·2–0·4) −41·4
Other skin and subcutaneous diseases <0·05 (0·0–0·05) <0·05 (0·0–0·05) −64·6 <0·05 (0·0–0·05) <0·05 (0·0–0·05) −69·8
Sudden infant death syndrome 3·8 (0·8–15·1) 1·6 (0·5–4·3) −49·6 0·3 (0·1–1·1) 0·2 (0·1–0·5) −26·8
Injuries 851·9 (738·8–968·8) 796·2 (697·4–992·5) –9·9 78·9 (68·7–89·3) 56·7 (49·8–70·4) –30·5
Transport injuries 159·5 (108·6–245·1) 287·0 (204·7–415·0) 79·0 14·7 (9·8–22·3) 19·8 (14·2–28·6) 33·5
Road injury 155·5 (105·5–231·8) 282·6 (205·2–414·9) 90·3 14·3 (9·7–21·2) 19·5 (14·2–28·6) 42·4
Pedestrian injury by road vehicle 34·7 (16·1–57·7) 105·4 (75·3–142·1) 188·9 3·2 (1·5–5·3) 7·2 (5·2–9·6) 113·8
Pedal cycle vehicle 6·0 (3·3–9·9) 8·8 (4·8–13·0) 48·2 0·6 (0·3–0·9) 0·6 (0·3–0·9) 11·2
Motorised vehicle with two wheels 33·2 (18·5–51·8) 48·7 (37·5–62·1) 48·6 3·0 (1·7–4·7) 3·3 (2·6–4·2) 12·4
Motorised vehicle with three or more wheels 34·5 (21·0–48·7) 74·0 (55·2–92·9) 111·5 3·1 (1·9–4·5) 5·1 (3·8–6·4) 59·8
Road injury other 47·1 (9·8–114·0) 45·7 (10·1–122·0) −5·8 4·4 (0·9–10·6) 3·2 (0·7–8·6) −28·0
Other transport injury 4·0 (1·9–6·5) 4·4 (2·5–7·2) 7·3 0·4 (0·2–0·6) 0·3 (0·2–0·5) −18·3
Unintentional injuries other than transport injuries 458·6 (412·0–508·7) 316·4 (277·2–349·5) −30·7 41·9 (38·2–46·4) 23·6 (20·7–26·1) −43·6
Falls 88·1 (75·4–109·8) 115·3 (89·1–136·0) 32·9 9·7 (8·2–12·2) 8·5 (6·6–10·0) −11·7
Drowning 147·4 (107·8–175·8) 67·4 (56·7–93·2) −56·5 12·2 (9·1–14·4) 5·5 (4·5–7·7) −57·4
Fire, heat, and hot substances 15·8 (12·7–19·9) 10·7 (8·4–15·4) −33·7 1·6 (1·3–2·0) 0·8 (0·6–1·2) −51·5
Poisonings 52·7 (39·6–93·6) 37·0 (19·3–49·0) −14·5 4·9 (3·7–8·8) 2·6 (1·4–3·4) −37·1
Exposure to mechanical forces 30·8 (23·1–44·0) 21·0 (12·2–27·0) −28·0 2·8 (2·1–4·1) 1·4 (0·8–1·8) −45·2
Mechanical forces (firearm) 11·4 (4·8–19·6) 3·6 (1·5–6·8) −69·3 1·0 (0·4–1·8) 0·2 (0·1–0·5) −76·2
Mechanical forces (other) 19·4 (9·3–36·9) 17·4 (7·1–28·0) −5·8 1·8 (0·8–3·4) 1·2 (0·5–1·9) −28·8
Adverse effects of medical treatment 4·2 (1·9–7·0) 7·0 (4·3–10·2) 72·4 0·4 (0·2–0·6) 0·5 (0·3–0·8) 34·1
Animal contact 8·0 (3·4–14·5) 3·0 (1·3–5·3) −61·7 0·8 (0·3–1·4) 0·2 (0·1–0·4) −71·0
Animal contact (venomous) 3·5 (1·2–9·1) 1·2 (0·5–2·5) −60·8 0·3 (0·1–0·9) 0·1 (0·0–0·2) −71·2
Animal contact (non-venomous) 4·5 (1·5–9·6) 1·8 (0·8–3·4) −59·3 0·4 (0·1–0·9) 0·1 (0·1–0·3) −68·1
Unintentional injuries not classified elsewhere 111·6 (81·2–128·8) 55·0 (39·9–62·4) −50·8 9·5 (7·0–10·8) 4·1 (3·1–4·7) −56·9
Self-harm and interpersonal violence 233·7 (157·5–278·0) 192·9 (152·2–309·3) −29·4 22·3 (15·4–26·7) 13·4 (10·5–21·3) −48·5
Self-harm 206·1 (132·3–248·9) 173·0 (134·6–286·0) −28·5 20·0 (13·1–24·6) 12·0 (9·3–19·7) −48·6
Interpersonal violence 27·7 (18·5–35·4) 19·9 (15·3–33·3) −36·0 2·3 (1·6–3·0) 1·4 (1·1–2·3) −47·0
Assault by firearm 4·9 (2·0–10·3) 2·2 (1·2–3·9) −54·7 0·4 (0·2–0·9) 0·1 (0·1–0·3) −63·8
Assault by sharp object 7·3 (3·6–12·0) 6·1 (3·9–9·7) −13·2 0·6 (0·3–1·0) 0·4 (0·3–0·7) −27·7
Assault by other means 15·5 (10·1–21·5) 11·7 (7·5–17·4) −23·9 1·3 (0·9–1·8) 0·8 (0·5–1·2) −36·9

Data are deaths (95% UI) or % change. 95% UIs are shown in parentheses. Percentage change is computed for 1000 draws of each quantity in 1990 and 2010 and median percentage change is reported. UI=uncertainty interval. DALYs=disability-adjusted life-years. %Δ=percentage change. E coli=Escherichia coli. H influenzae=Haemophilus influenzae.