. 2007 Sep 27;370(9593):1137–1145. doi: 10.1016/S0140-6736(07)61515-3

Table 1.

Results of in-situ hybridisation and immunohistochemistry in selected organs and cell types

	Patient 1		Patient 2		Fetus
	ISH^*	IHC^†	ISH	IHC	ISH	IHC
Trachea	+/+	+/+	+/+	+/+	..	..
Bronchi	−/−	−/−	−/−	−/−	+/+	+/+
Alveolar pneumocytes	+/+	+/+	−/−	−/−	+/+	+/+
Lymph nodes	+/+^‡	..	+/+^‡	+/+^‡	..	..
Spleen	−/−	−/−	−/−	−/−	..	..
Heart	−/−	−/−	−/−	−/−	−/−	−/−
Endothelial cells	−/−	−/−	−/−	−/−	−/−	−/−
Hepatocytes	−/−	−/−	−/−	−/−	−/−	..
Kupffer cells	−/−	−/−	−/−	−/−	+/+	..
Kidneys	−/−	−/−	−/−	−/−	−/−	..
Small intestine	+/+	−/−	+/+	−/−	−/−	..
Brain	..	..	+/+	+/+	..	..
Syncytiotrophoblasts	−/−	−/−	n/a	n/a	n/a	n/a
Cytotrophoblasts	+/+	+/+	n/a	n/a	n/a	n/a
Hofbauer cells	+/+	+/+	n/a	n/a	n/a	n/a
Circulating mononuclear cells	−/−	−/−	−/−	+/+	+/+	+/+

ISH=in-situ hybridisation. IHC=immunohistochemistry. n/a=not applicable. Plus sign=positive. Minus sign=negative.

Results presented for sense/antisense probes (identical results for nucleoprotein and haemagglutinin).

^†

Results presented for nucleoprotein/haemagglutinin signals (nucleoprotein mainly detected in nucleus and haemagglutinin in cytoplasm).

^‡

Includes putative T lymphocytes.