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. 2016 Nov 8;389(10067):403–476. doi: 10.1016/S0140-6736(16)31599-9

Table 4.

Pro-generic policies to increase competition and reduce prices162

Description or examples
Supply side
Preventing delay in generic entry Expedited or abbreviated application processes, early working (Bolar) provisions, and biowaivers
Incentivising market authorisation Incentives for manufacturers to file an application for market authorisation of a generic medicine
Assuring quality of generic medicines Requirements for bioequivalence testing and the publication of lists of interchangeable medicines; transparency of reviews of such evidence; reliance on decisions taken by stringent regulators or prequalification
Using TRIPS flexibility Policies that enable the use of TRIPS flexibilities, including undisclosed test data protection that does not prohibit the registration of a generic
Increasing competition between manufacturers Patent pools, improving transparency of patent information, and publishing information on the prices of medicines
Pricing for affordability Internal reference pricing, external reference pricing, pricing controls, the regulation of distribution chain mark-ups, and charges; pooled procurement and tenders
Demand side
Promoting generic prescribing Prescribing medicines by the international non-proprietary (generic) name
Enabling substitutions Mandate or enable the dispensing of generic equivalents instead of branded products by pharmacists and other dispensers
Adapting medicines reimbursement policies Promoting generic medicines via waiver of copayments or the application of internal reference pricing
Promoting independent medicines information Banning the provision of free medicine samples, banning direct-to-consumer advertising of prescription medicines
Monitoring consumption Monitor and report the consumption pattern of generic medicines

TRIPS=Trade-Related Aspects of Intellectual Property Rights.