Table 1.
Summary of allorecognition systems in N. crassa. The right column shows the cumulative calculation of the total number of incompatible groups identified so far. The estimated total of incompatible genotypes is indicated in bold.
| Asexual stage | Cell-cell fusion step | Allorecognition reaction | Loci | References | Number of haplogroups | Cumulative number of incompatible genotypes |
|---|---|---|---|---|---|---|
| Germling and hyphal | Intercellular communication and chemotropism | Avoidance at distance | doc | [18] | 5 | 5 |
| Cell wall remodeling | Arrest and cell wall accumulation upon contact | cwr | [19] | 6 | 30 (5 x 6) | |
| Cytoplasmic mixing | Cell death | sec-9/plp-1 | [20] | 4 | 120 (30 x 4) | |
| rcd-1 | [21] | 2 | 240 (120 x 2) | |||
| Hyphal (het loci) | Cytoplasmic mixing | Cell death | het-e | [22] | 3 | 720 (240 x 3) |
| het-c/pin-c | [24] | 3 | 2160 (720 x 3) | |||
| mat/tol | [25] | 2 | 4320 (2,160 x 2) | |||
| 9 additional het loci | [24,26–28] | 29 * | 2,211,840 (4320 x 29) |
* Two haplotypes were conservatively assumed since a systematic analysis of wild populations has not been performed.