Table 1.
Clinical scoring of pristane‐induced arthritis in parental rat strains
| Strain | No. of rats | Incidence of arthritis, % | Maximum clinical score, mean ± SD* | No. of affected paws, mean ± SD† | Cumulative score, mean ± SD‡ | Arthritis onset, mean ± SD days | Incidence of tail ankylosis, % |
|---|---|---|---|---|---|---|---|
| DA | 10 | 100 | 31 ± 14 | 3.7 ± 0.5 | 370 ± 282 | 14 ± 1 | 75 |
| E3 | 10 | 0 | 0 | 0 | 0 | – | 0 |
| LEW.1F | 11 | 100 | 37 ± 13 | 3.4 ± 0.7 | 423 ± 174 | 17 ± 3 | 0 |
Arthritis severity was evaluated as described in Materials and Methods (maximum score per rat 60). The maximum clinical score is the value for each rat at the time of the most severe arthritis.
Mean number of paws per rat with clinical signs of arthritis at the time of the most severe arthritis.
Total of arthritis scores for all scoring done during the experiment.