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Protein epitope signature tags (PrESTs: protein sequences large enough to contain good epitopes but small enough for expression in Escherichia coli) are generated by careful computer‐assisted selection. After PrEST expression and host immunization, the obtained polyclonal antibody is purified carefully by affinity purification with the corresponding PrEST to give a high‐quality, monospecific antibody.26 Reproduced from reference 26.
