Table 3.

Sensitivities of 2 and selected anti‐HIV agents against HIV‐1_Ba‐L, HIV‐2_ROD, and HIV‐2_EHO.

Virus		Mean IC50 [nm][a]
	Cell type	SQV	RTV	IDV	NFV	APV	AZT	DRV (2)
HIV‐1Ba‐L	PBMC	18	39	25	17	26	9	3
HIV‐2ROD	MT‐2	3	130	14	19	230	18	3
HIV‐2EHO	MT‐2	6	240	11	29	170	11	6

[a] All assays were conducted in duplicate or triplicate; the data represent mean IC₅₀ values from three independent experiments. IC₅₀ were evaluated with PHA‐PBMC and the inhibition of p24 Gag protein production by the drug as an end point. MT‐2 cells were exposed to the virus and cultured, and IC₅₀ values were determined by MTT assay. See references 82 and 105 for details.