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Diversity of cyclic peptides. a) Cyclic peptides occur in bacteria, plants, animals, and fungi. b) They vary in their sequences, size, and disulfide connectivities. Amino acid sequences of AS‐48, kalata B1, RTD‐1, and α‐amanitin with disulfide bonds as grey lines and post‐translationally modified residues marked with an asterisk. c) Three‐dimensional structures of AS‐48 (PDB 1E68),5 kalata B1 (PDB 1NB1),6 RTD‐1 (PDB 2LYF),7 and α‐amanitin (PDB 1K83)8 shown as cartoons.
