Figure 2.

Mammalian defensins. a) Mammalian defensins are divided into three classes, α‐defensins (e.g. HNP‐4), β‐defensins (e.g. HBD‐3), and θ‐defensins (e.g. HTD‐2). Amino acids are represented by their one‐letter codes, grey lines represent disulfide bonds and disulfide connectivities are shown by Roman numerals. b) Three‐dimensional structures of HNP‐4 (PDB 1ZMM),56 HBD‐3 (PDB 1KJ6),58 and retrocyclin‐2 (PDB 2ATG)60 are shown in cartoon representation with disulfide bonds in grey.