Table 2.

Characteristics and clinical findings for each patient in the apnoea group

Patient	Age in months	GA/BW	Medical history	Parental reported apnoea	Description of clinically observed apnoea	Maximum desaturation (%)	Bradycardia (beats/min)	Diagnosis at discharge	PICU	LOS	DSS	PCR results
1	0.95	39 5/7 3865	No	Absence of breathing for 15 seconds after vomiting during breastfeeding. Self‐correcting	None	–h	–	ARI/GERDc	No	2	3	Neg
2	1.7	39 1/7 4210	No	Recurring periods of the absence of breathing after coughing. Cyanosis of lips. Recovery after moderate stimulation	Paroxysmal coughing	79	–	ARI	No	8	12	IVd BPe
3	0.72	37 2/7 3085	No	Absence of breathing for 15–20 seconds	Recurring absent breathing CPAP and caffeine during PICU admission	65	50	ARI	Yes	2	15	HBoVf
4	0.33	39 5/7 3440	No	Absence of breathing for several seconds	Absent breathing in emergency room. Severe dyspnoea	85	–	Bronchiolitis	No	10	27	RSV
5	0.62	36 6/7 2835	Yesa	Hypotonia and alarm on sleep apnoea baby pad activated four times. Recovery after moderate stimulation	Multichannel registration: short central apnoeas	86	–	ARI/GERDc	No	7	9	Neg
6	2.13	36 3/7 3125	No	None reported	Detoriation of respiratory condition and apnoeas. Mechanical ventilation during PICU admission	–	–	Bronchiolitis Pneumonia	Yes	10	26	RSV HCoVg
7	0.23	40 0/7 2640	No	Recurring episodes of hypotonia and cyanosis of the face. Self‐correcting	None. Desaturation during sleep	89	–	–	No	2	4	Neg
8	0.23	40 3/7 3360	No	Cyanosis of the face	Rapid detoriation of respiratory condition and apnoeas	55	50	Sepsis	No	10	4	Neg
9	0.69	42 0/7 4480	No	None reported	Three episodes of absent breathing after coughing Severe mucus production	73	–	Bronchiolitis	No	6	16	RSV
10	2.79	41 3/7 4000	No	Cyanosis of the face during feeding	None	–	–	Bronchiolitis	No	4	11	RSV
11	2.43	36 4/7 2890	No	Three episodes of absent breathing for several seconds. Somnolence	Frequent episodes of absent breathing for several seconds. Severe mucus production and coughing	85	–	Bronchiolitis Pneumonia	No	6	15	RSV
12	0.95	40 4/7 3600	No	Recurring episodes of absent breathing. Cyanosis of the face and somnolence. Recovery after moderate stimulation	Absent breathing for several seconds. Exhaustion. No mechanical ventilation during PICU admission	87	60	Bronchiolitis Pneumonia	Yes	6	27	RSV
13	1.08	35 5/7 2693	No	Three episodes of cyanosis of the face after coughing. Self‐correcting	Several episodes of absent breathing for several seconds. Cyanosis of the face. Coughing	66	–	ARI	No	7	21	Neg
14	1.05	33 1/7 2390	No	Cyanosis of the face	Detoriation of respiratory condition and apnoeas. Mechanical ventilation during PICU admission	38	–	Bronchiolitis	Yes	15	27	RSV
15	2.46	39 1/7 3475	Yesb	Absence of breathing several seconds. Hypotonia and somnolence	Five episodes of absent breathing during sleep and during feeding	76	80	Bronchiolitis	No	1	16	Neg
16	0.66	36 6/7 3060	No	Cyanosis of the face	Recurring periods of absent breathing for several seconds. Recovery after moderate stimulation	72	79	ARI	No	7	11	HCoV
17	1.05	36 6/7 3080	No	Rhinitis, short period of absent breathing	No clinical admission. Excellent condition during observation in emergency room	–	–	ARI	No	–	11	HRV
18	1.9	40 0/7 3270	No	Two episodes of absent breathing for several seconds after coughing. Recovery after moderate stimulation	Two episodes of absent breathing for several seconds. Cyanosis of the face. Recovery after moderate stimulation	86	50	Bronchiolitis	No	4	16	RSV
19	0.52	38 0/7 2460	No	Absent breathing for 15–20 seconds. Pale face	None. Superficially breathing pattern	87	–	ARI, Premature breathing pattern	No	1	9	Neg

^aPremature breathing with apnoeas first days of live; caffeine therapy.

^bRSV bronchiolitis at age six weeks; mechanical ventilation for one week.

^cGERD: gastro‐oesophageal reflux disease.

^dInfluenza virus.

^e Bordetella Pertussis.

^fHuman Bocavirus.

^gHuman Coronavirus.

^hMissing data.