Table 1.
Clinical arthritis in parental rat strains and segregating crosses of rats with CIA and PIA*
| No. of rats | Day of arthritis onset, mean ± SEM | Maximum clinical score, mean ± SEM | Incidence, % | |
|---|---|---|---|---|
| Rats with CIA | ||||
| E3 | 9 | – | – | 0 |
| DA | 18 | 22 ± 5 | 19 ± 1 | 78 |
| (E3 × DA)F1 | 18 | – | – | 0 |
| (E3 × DA)DA | 364 | 26 ± 1 | 8 ± 1 | 34 |
| Rats with PIA | ||||
| E3 | 10 | – | – | 0 |
| DA | 104 | 12 ± 0.2 | 32 ± 0.7 | 100 |
| (E3 × DA)F1 | 82 | 23 ± 1.0 | 9 ± 1.1 | 59 |
| (E3 × DA)DA | 650 | 16 ± 0.2 | 14 ± 0.6 | 70 |
*
Values are the mean ± SEM. CIA = type II collagen–induced arthritis; PIA = pristane‐induced arthritis.