Table 1.

Research priority areas of National Institute on Drug Abuse (NIDA) and National Center for Advancing Translational Science (NCATS)

Research domain	Priority areas
Pain management (safe and more effective strategies)	Non-opioid analgesics: cannabinoids, anti-inflammatory medications, ion channel blockers
	Targeted opioid analgesics
	Biologics: antibodies that bind to pain producing cytokines
	Non-pharmacologic treatments: Neural stimulation; surgical intervention, meditation, etc.
Opioid addiction treatment (new and innovative medications and technologies)	Mapping differences in the brain
	Medication-assisted treatment (MAT)
	Emergency department initiated buprenorphine
	Naltrexone treatment for criminal justice populations
	Fentanyl vaccine
Overdose reversal (interventions to reduce mortality and linkage to treatment)	More widespread naloxone distribution
	Stronger, longer acting formulations for more potent opioids
	Devices to stop respiratory depression
	Overdose detection and alert technologies
	Linkage to treatment after over dose (OD)