Table 1. The phosphorylation sites of p65, and responsible kinases.

Acetylation sites of p65 and the corresponding enzymes;

* Recently discovered phosphorylation sites

Site	Location	Kinase	Function	Reference
Ser 205*	RHD	unknown	Transcriptional activity	66
Ser 276	RHD	PKAc MSK1	Transcriptional activity Captivator binding Transcriptional activity	67,68
Ser 281*	RHD	unknown	Transcriptional activity	66
Ser 311	RHD	PKCz	Transcriptional activity	69
Ser 468	TA2	GSK3β IKKβ IKKα	Transcriptional activity Transcriptional activity Transcriptional activity	70-72
Ser 529	TA1	CK II	Transcriptional activity	73
Ser 535	TA1	CaMKIV	Transcriptional activity	74
Ser 536	TA1	IKKα IKKβ IKKe TBK1 RSK1	Transcriptional activity and stabilization Transcriptional activity and nuclear import Transcriptional activity Nuclear localization Affinity to IκBα	75-81
Ser 547*	unknown	ATM-DSB	Transcriptional inhibition of target genes by HDAC recruitment	82
Thr 254*	RHD	unknown	Stabilization and Nuclear localization	83
Thr 435*	TA2	unknown	Transcriptional activity	84
Thr 505	TA2	ATR ChK1	Transcriptional activity	85,86
Tyr 66 Tyr 152	RHD	NO treatment	p65 dissociation from p50 and association with IκBα	87
Site	Location	Enzyme	Function	Reference
Lys 122	RHD	P300, PCAF	Inhibition DNA binding	88
Lys 123	RHD	P300, PCAF	Inhibition DNA binding	88
Lys 218	RHD	CBP/p300	Unknown	89
Lys 221	RHD	CBP/p300	Promoting DNA binding Inhibition IκBα binding	89
Lys 310	RHD	CBP/p300	Enhancing transactivation	89
Lys 314	RHD	P300	Transcriptional activity	90
Lys 215	RHD	P300	Transcriptional activity	90