Figure 5. Relationship between scalp EEG beta bursts and CancelTime (study 4 and 5).

(a) Burst % across time for Successful Stop (red), Failed Stop (orange), and Correct Go (green) trials for an exemplar participant in study 4 from the right frontal spatial filter. The shaded region represents mean ± s.e.m. The CancelTime is shown in brown and the SSRTBeh as a cyan line. (b) The mean burst probability across all participants for Successful Stop (red), Failed Stop (orange), and Correct Go (green) trials and their respective baselines (gray). The bars and cross-hairs represent the mean and s.e.m across participants, while the dots represent individual participants. (Inset top right) The average scalp topography of all the right frontal ICs across all participants. (c) Same as (b) but for study 5. (d) Correlation between mean BurstTime and mean CancelTime. The yellow dots and cross-hairs represent the participants in study 4, while the light red ones represent participants in study 5. The brown line and the shaded area represent the linear regression fit and its 95% confidence interval (pooled study 4 and 5). Other details same as Figure 2d.

Figure 5—figure supplement 1. Beta power in Successful Stop trials for study 4.

(a–k) shows the time course of the peak beta power (solid red line) in the selected IC for each participant. The dotted cyan line represents each participant's SSRT_Beh. The inset in each panel shows the scalp topography for the selected IC.

Figure 5—figure supplement 2. Average dipole location of the ICs selected in study 4 and 5.

(a), (b), and (c) The sagittal, top, and coronal view of the brain respectively, showing the average dipole location. The purple dot represents the mean location and the orange bubble represents the SD.

Figure 5—figure supplement 3. Illustration of beta burst computation.

(a) The average beta power (13–30 Hz) between the Stop signal and SSRT_Beh (top panel) for a participant. The window between mean SSD (dotted pink line) and Stop (dotted black line at 0) represents the baseline time window (BaseWin). The time from Stop signal to SSRT_Beh (dotted cyan line) represents the stop time window (StopWin). The burst threshold window is the time period from 500 to 1000 ms after the Stop signal. The bottom two panels show single trial examples of brief bursts of activity with the dotted black and cyan lines represent the Stop signal and SSRT_Beh respectively. (b) The histogram of beta amplitude for all trials in a participant i(500 to 1000 ms after the Stop signal in the Stop trials; 500 to 1000 ms after mean SSD in the Go trials). The dotted red line represents the threshold for defining a burst which is estimated as median + 1.5 SD of the beta amplitude. The BurstTime and burst height are the time and amplitude of the peak within a burst respectively. Once a burst is identified using this threshold, the burst % and burst length are estimated using a lower threshold which is median + SD (dotted blue line) (c) The burst raster for all trials in a participant across time. Each black dot represents a burst in that trial. To compute BurstTime we consider the burst times between the Stop signal and SSRT_Beh (dotted cyan line).

Figure 5—figure supplement 4. Dynamics of burst% aligned to the Go cue.

(a) Burst% for the Correct Go (green), Successful Stop (red), and Failed Stop (orange), aligned to the Go cue in Study 4. The bold traces represent the mean across the population, while the shaded region represents the s.e.m. The grey, brown, and cyan shaded regions represent the mean ± s.e.m. of the time of presentation of the Stop signal, CancelTime, SSRT_Beh across the population. (b) Same as (a) but for Study 5.

Figure 5—figure supplement 5. Relationship of CancelTime with other burst parameters.

(a) Correlation between mean burst height (0.9 ± 0.2) and mean CancelTime across participants in study 4 (r = 0.5, p=0.161, BF₁₀ = 0.7). The brown dots and cross-hairs represent the mean ± s.e.m. for individual participants. The brown line and the shaded area represent the linear regression fit and its 95% confidence interval respectively. (b) Across participants correlation between mean burst length (210 ± 20 ms) and mean CancelTime in study 4 (r = −0.1, p=0.801, BF₁₀ = 0.3). Other details are same as in (a). (c) Same as (a) but for study 5. Mean burst height is 0.65 ± 0.05 (r = −0.3, p=0.281, BF₁₀ = 0.5). (d) Same as (b) but for study 5. Mean burst length is 220 ± 15 ms (r = −0.22, p=0.475, BF₁₀ = 0.4).