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. 2020 Apr 15;40(16):3165–3177. doi: 10.1523/JNEUROSCI.0155-20.2020

Figure 6.

Figure 6.

Early-onset obesity, increased linear growth, and glucose intolerance in Prdm12POMCeKO mice. A–C, Body weight and body composition (16-week-old) of female Prdm12POMCeKO mice. D–G, H&E staining in the liver and in inguinal white adipose tissue (iWAT) of HFD-fed female mice. Scale bars: D, E, 50 µm; F, G, 100 µm. Body length of female Prdm12POMCeKO mice. I, J, GTT of HFD-fed mice. K, Serum insulin levels during GTT. L, ITT of HFD-fed mice. *p < 0.05; **p < 0.01; ***p < 0.001; unpaired t test (A, H); two-way ANOVA with Sidak's tests for (B, C, I–L).