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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Parkinsonism Relat Disord. 2020 Feb 17;72:37–43. doi: 10.1016/j.parkreldis.2020.02.004

Table 2.

The influence of ethnicity on age at onset and severity of ataxia in SCA3 via multivariate linear regression

Age at onset
Coefficient (β) Standard error p-value
Gender (M vs. F) −1.37 0.98 0.163
Length of expanded CAG repeats in ATXN3, N −2.16 0.12 0.000
Length of normal CAG repeats in ATXN3, N 0.05 0.08 0.509
Ethnicity (Caucasians vs. African Americans) 1.88 1.55 0.226
Ethnicity (Asians vs. Caucasians) 4.75 1.25 0.000
Ethnicity (Asians vs. African Americans) 6.64 1.45 0.000
Severity of ataxia
Coefficient (β) Standard error p-value
Gender (M vs. F) 0.03 0.84 0.973
Age at first visit, Yr 0.40 0.06 0.000
Disease duration, Yr 0.47 0.08 0.000
Length of expanded CAG repeats, N 1.09 0.16 0.000
Length of normal CAG repeats, N −0.02 0.07 0.783
Ethnicity (Caucasians vs. African Americans) −3.81 1.31 0.004
Ethnicity (Asians vs. Caucasians) −0.59 1.11 0.597
Ethnicity (Asians vs. African Americans) −4.39 1.30 0.001

Abbreviations: F = Female, M = Male, N = Number, SCA = Spinocerebellar Ataxia, Yr = Year.