Table 3.
The rate (%) of non-ataxia manifestations in SCA3 participants
| Caucasian N = 66 |
African American N = 43 |
Asian American# N = 17 |
p-value a | |
|---|---|---|---|---|
| Dystonia | 0.046 | |||
| Yes | 16 (24.24) | 15 (34.88) | 1 (5.88) | |
| No | 50 (75.76) | 28 (65.12) | 16 (94.12) | |
| Postural tremor | 0.175 | |||
| Yes | 9 (13.64) | 5 (11.63) | 0 (0.00) | |
| No | 57 (86.36) | 38 (88.37) | 17 (100.00) | |
| Depression (PHQ9 > = 10) | 0.357 | |||
| Yes | 23 (34.85) | 12 (27.91) | 3 (17.65) | |
| No | 43 (65.15) | 31 (88.37) | 14 (82.35) | |
| Peripheral neuropathy | 0.953 | |||
| Yes | 37 (56.06) | 23 (53.49) | 9 (52.94) | |
| No | 29 (43.94) | 20 (46.51) | 8 (47.06) | |
| Restless legs syndrome | 0.366 | |||
| Yes | 6 (9.09) | 1 (2.33) | 1 (5.88) | |
| No | 60 (90.91) | 42 (97.67) | 16 (94.12) |
Abbreviations: SCA = Spinocerebellar Ataxia.
#
All 17 SCA3 patients are from the CRC-SCA cohort.
a
Chi-square test