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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Addict Biol. 2019 Oct 16;25(6):e12831. doi: 10.1111/adb.12831

Figure 4.

Figure 4.

(A) Group*region*condition interaction results for insular blood-oxygen-level dependent (BOLD) percent signal change (PSC) from baseline. SUD = current stimulant use disorder. OUD = current opioid use disorder. CTL = healthy comparisons. The blue stars indicates a significant difference for SUD versus CTL, whereas the red star indicates a significant difference for OUD versus CTL. Error bars reflect +/− 1 standard error. (B) Within SUD, greater past-year stimulant use was associated with higher dorsal dysgranular insula BOLD signal during the heart condition, sharing 11% of the variance.