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. 2020 Apr 15;10:6436. doi: 10.1038/s41598-020-63475-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Random forest using (a) functional subroles and (b) TIGRFAM as discriminatory variables. The colour indicates the enrichment in NT (red) or HT (blue) based on the log2 fold change between the relative abundance average of NT group and the relative abundance average of HT group. Length of bars represents the discriminatory power of the variables.