Table 3.
Summary for the functions of important candidate genes at QTL region. Genes are searched within approximately ± 20Kb region of the significant SNPs, and detected candidate genes might be playing role in variation for AGD phenotype.
| Ssa | SNP | Annotation | Genes (~ ± 20 Kb) | Description | Ref |
|---|---|---|---|---|---|
| 02 | AX-88266207 | Intronic | tnxb.b | This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. This protein is thought to function in matrix maturation during wound healing. | 41 |
| slc45a4 | Solute carrier family 45, member 4, found to be functioning as sucrose transporter | 54 | |||
| c4 | It is central to the activation of both the classical and the lectin pathways of complement activation. The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear pathogens from an organism. | 45 | |||
| 05 | AX-87970438 | Intronic | slc44a4 | Solute carrier family 44 member 4 involved in the uptake of choline by cholinergic neurons. | 41 |
| ano10a | The transmembrane protein encoded by this gene is a member of a family of calcium-activated chloride channels. | 41 | |||
| 01 | AX-87017245 | 3’UTR | kcng3 | Potassium voltage-gated channel modifier subfamily G member 3. It is diverse in functionality includes epithelial electrolyte transport, heart rate etc. | 55 |