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. 2020 Apr 15;11:1842. doi: 10.1038/s41467-020-15707-w

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© The Author(s) 2020, corrected publication 2022

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Fig. 2 — X-axis: annotation class. Y-axis: odds ratio. Legend: exomes: coding variants in all genes; LOFtol: in genes tolerant to loss-of-function variation; LOFintol: in genes intolerant to loss-of-function variation. For each specific burden test, we used a vertical line to indicate the 95% confidence interval of odds ratio and a dot at the center of the vertical line to indicate the point estimate of odds ratio.