Table 2.
Association between Metabolic Parameters and Incidence Rate of Bladder Cancer.
| n | Event | Duration (person-years) | IR (per 1000 person-years) | Multivariable-adjusted HR * (95% CI) | |
|---|---|---|---|---|---|
| BMI, kg/m2 | |||||
| <18.5 | 280,457 | 573 | 1,451,988.41 | 0.39463 | 0.968 (0.889–1.055) |
| 18.5–23 | 3,970,603 | 6,052 | 21,405,151.08 | 0.28274 | 1 (ref.) |
| 23–25 | 3,147,316 | 4,914 | 17,099,066.95 | 0.28738 | 1.085 (1.045–1.127) |
| 25–30 | 3,934,367 | 5,825 | 21,279,792.75 | 0.27373 | 1.156 (1.115–1.199) |
| >30 | 449,025 | 413 | 2,374,578.85 | 0.17393 | 1.146 (1.037–1.267) |
| WC, cm | |||||
| <90 | 9,155,550 | 12,411 | 49,532,933.98 | 0.25056 | 1 (ref.) |
| ≥90 | 2,626,218 | 5,366 | 14,077,644.07 | 0.38117 | 1.217 (1.178–1.256) |
| HTN | |||||
| No | 5,942,325 | 5,647 | 32,204,726.79 | 0.17535 | 1 (ref.) |
| Yes | 5,839,443 | 12,130 | 31,405,851.26 | 0.38623 | 1.106 (1.071–1.142) |
| DM | |||||
| No | 7,487,275 | 8,976 | 40,615,361.53 | 0.221 | 1 (ref.) |
| Yes | 4,294,493 | 8,801 | 22,995,216.52 | 0.38273 | 1.12 (1.087–1.154) |
| High TG | |||||
| No | 6,848,357 | 9,372 | 36,955,739 | 0.2536 | 1 (ref.) |
| Yes | 4,933,411 | 8,405 | 26,654,839.05 | 0.31533 | 1.178 (1.144–1.213) |
| Low HDL | |||||
| No | 9,180,364 | 11,784 | 49,671,734.08 | 0.23724 | 1 (ref.) |
| Yes | 2,601,404 | 5,993 | 13,938,843.97 | 0.42995 | 1.199 (1.162–1.237) |
| MO | |||||
| No | 8,483,442 | 10,151 | 45,964,233.99 | 0.22085 | 1 (ref.) |
| Yes | 3,298,326 | 7,626 | 17,646,344.06 | 0.43216 | 1.224 (1.188–1.261) |
Abbreviations: IR, incidence rate; HR, hazard ratio; CI, confidence interval; BMI, body mass index; WC, waist circumference; HTN, hypertension; DM, diabetes mellitus; TG, triglyceride; LDL, low-density lipoprotein; MO, metabolically obese.
*Adjusted for age, smoking, alcohol drinking, exercise, and income.