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. 2020 Jan 31;30(5):2680–2691. doi: 10.1007/s00330-019-06597-8

Table 4.

The detailed AUC values and p values among models on the three datasets

Dataset Model AUC 95% CI P1 P2 P3
Training Clinical 0.58 0.52–0.65 < 0.01*
Semantic 0.85 0.81–0.89 0.01*
Volume 0.84 0.80–0.88 0.01*
FS 0.90 0.87–0.93 0.82 0.58 < 0.01*
Radiomics 0.89 0.86–0.93
RV 0.90 0.87–0.94 0.18 < 0.01*
CSRV 0.91 0.88–0.94
FSV 0.94 0.91–0.96 0.06
FSRV 0.96 0.94–0.98
CSFSRV 0.96 0.94–0.98 < 0.01* 0.74
Testing Clinical 0.55 0.45–0.65 < 0.01*
Semantic 0.85 0.78–0.92 0.28
Volume 0.87 0.81–0.93 0.54
FS 0.93 0.88–0.97 0.20 0.21 0.01*
Radiomics 0.89 0.83–0.94
RV 0.88 0.82–0.93 0.10 < 0.01*
CSRV 0.89 0.84–0.94 0.21
FSV 0.98 0.96–1 0.50
FSRV 0.97 0.94–1
CSFSRV 0.97 0.94–0.99 < 0.01* 0.25
Validation Clinical 0.61 0.51–0.72 < 0.01*
Semantic 0.87 0.81–0.92 0.75
Volume 0.93 0.88–0.98 0.16
FS 0.92 0.87–0.96 0.29 0.97 0.01*
Radiomics 0.88 0.81–0.94
RV 0.91 0.86–0.96 0.71 0.03*
CSRV 0.92 0.87–0.96
FSV 0.97 0.94–0.99 0.62
FSRV 0.96 0.93–0.99
CSFSRV 0.96 0.94–0.99 0.01* 0.30

FS, frozen section; RV, radiomics combining with volume; CSRV, radiomics combing with clinical, semantic, and volume; FSV, frozen section combining with volume; FSRV, frozen section combining with radiomics and volume; CSFSRV, radiomics combining with clinical, semantic, volume, and frozen section; AUC, the area under the curve; CI, confidence interval. *p < 0.05; P1 = p values between radiomics and other models; P2 = p values between CSRV and other models; P3 = p values between FSRV and other models. p values calculated using roc test by Delong method