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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Cardiol Clin. 2020 Mar 2;38(2):185–202. doi: 10.1016/j.ccl.2020.01.004

Table 1.

Types of Cardio-renal syndrome (CRS)

Type of CRS Definition Conditions
Type 1: Acute CRS Acute worsening of heart function leading to kidney injury and/or dysfunction Acute HF, Acute cardiogenic shock
Type 2: Chronic CRS Chronic abnormalities in heart function leading to progressive and permanent CKD Chronic HF
Type 3: Acute Renocardiac syndrome AKI causing acute heart dysfunction Acute glomerunephritis/ AKI cause acute HF,
Type 4: Chronic Renocardiac syndrome CKD leading to chronic heart disease and CKD progression CKD cause cardiac hypertrophy, decreased cardiac function
Type 5: Secondary CRS Systemic diseases leading to heart and kidney damage/dysfunction Diabetes, sepsis, septic shock

CRS: Cardio Renal Syndrome, HF: Heart failure, AKI: Acute Kidney Injury, CKD: Chronic Kidney damage