Table 2.
Events graded as NT by CTCAE, but not mCRES and ASTCT
| Event | Number of patients | Maximal grade of event | Onset, d from infusion |
|---|---|---|---|
| Headache*† | 20 | 2 | 1, 1, 1, 2, 2, 2, 2, 3, 3, 4, 5, 5, 6, 7, 8, 9, 18, 28, 63, 195 |
| Anxiety* | 7 | 3 | 1, 1, 2, 3, 8, 22, 289 |
| Dizziness* | 7 | 1 | 1, 4, 5‡, 6, 9, 10, 19, 28‡ |
| Insomnia*† | 4 | 2 | 4, 6, 8, 18 |
| Dysphagia*† | 2 | 3 | 2, 10 |
| Syncope | 2 | 3 | 1, 346 |
| Depression | 1 | 1 | 1 |
| Disturbance in attention* | 1 | 2 | 8 |
| Dysgeusia* | 1 | 1 | 7 |
| Horner’s syndrome*† | 1 | 1 | 11 |
| Hypoesthesia* | 1 | 1 | 138 |
| Hypotonia | 1 | 1 | 4 |
| Mental status changes | 1 | 3 | 323 |
| Migraine* | 1 | 2 | 4 |
| Nerve compression*† | 1 | 3 | 279 |
| Neuralgia*† | 1 | 2 | 32 |
| Paraesthesia*† | 1 | 1 | 12 |
| Peripheral sensory neuropathy* | 1 | 1 | 18 |
| Polyneuropathy*† | 1 | 3 | 4 |
| Tearfulness* | 1 | 2 | 5 |
| Tremor* | 1 | 1 | 17 |
| VIth nerve paralysis*† | 1 | 3 | 10 |
*
Event was observed at least once in a patient with CRS per Penn grade.
†
Event occurred at least once in a patient with severe (grade 3-4) CRS per Penn grade.
‡
Event occurred twice in same patient.