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. 2020 Apr 8;4(7):1350–1356. doi: 10.1182/bloodadvances.2019001284

Table 4.

Multivariate analysis of donor KIR models and transplant outcomes

End points Donor KIR haplotype, AA vs Bx Donor KIR Cen regions score, AA vs AB vs BB Donor KIR Tel regions score, AA vs AB vs BB Donor KIR B content score, neutral vs better vs best Donor KIR B content score, 1 vs 2 vs 3 vs 4 Alternative donor KIR B content score, 0-1 vs 2 ≤ KIR B composite score, 4 vs 3 vs 2 KIR2DS1 score, no vs yes
Survival P = .78 P = .38 P = .54 P = .42 P = .89 P = .67 P = .28 P = .33
AA, n = 240 AA, n = 354 AA, n = 424 Neutral, n = 491 0, n = 240 0-1, n = 491 2, n = 184 No, n = 438
Bx, n = 473 AB, n = 292 AB, n = 246 Better, n = 155 1, n = 251 2+, n = 222 3, n = 415 Yes, n = 275
BB, n = 67 BB, n = 43 Best, n = 67 2, n = 169 4, n = 114
3+, n = 53
DFS P = .67 P = .36 P = .16 P = .28 P = .96 P = .98 P = .22 P = .71
AA, n = 238 AA, n = 350 AA, n = 421 Neutral, n = 488 0, n = 238 0-1, n = 488 2, n = 183 No, n = 432
Bx, n = 468 AB, n = 289 AB, n = 244 Better, n = 151 1, n = 250 2+, n = 218 3, n = 411 Yes, n = 274
BB, n = 67 BB, n = 41 Best, n = 67 2, n = 165 4, n = 112
3+, n = 53
TRM P = .46 P = .09 P = .35 P = .08 P = .61 P = .61 P = .19 P = .55
AA, n = 238 AA, n = 350 AA, n = 421 Neutral, n = 488 0, n = 238 0-1, n = 488 2, n = 183 No, n = 432
Bx, n = 468 AB, n = 289 AB, n = 244 Better, n = 151 1, n = 250 2+, n = 218 3, n = 411 Yes, n = 274
BB, n = 67 BB, n = 41 Best, n = 67 2, n = 165 4, n = 112
3+, n = 53
Relapse P = .46 P = .82 P = .13 P = .76 P = .86 P = .46 P = .71 P = .73
AA, n = 238 AA, n = 350 AA, n = 421 Neutral, n = 488 0, n = 238 0-1, n = 488 2, n = 183 No, n = 432
Bx, n = 468 AB, n = 289 AB, n = 244 Better, n = 151 1, n = 250 2+, n = 218 3, n = 411 Yes, n = 274
BB, n = 67 BB, n = 41 Best, n = 67 2, n = 165 4, n = 112
3+, n = 53
aGVHD II-IV P = .79 P = .54 P = .73 P = .33 P = .21 P = .46 P = .90 P = .09
AA, n = 191 AA, n = 271 AA, n = 326 Neutral, n = 369 0, n = 191 0-1, n = 369 2, n = 135 No, n = 329
Bx, n = 344 AB, n = 212 AB, n = 182 Better, n = 114 1, n = 178 2+, n = 166 3, n = 320 Yes, n = 206
BB, n = 52 BB, n = 27 Best, n = 52 2, n = 129 4, n = 80
3+, n = 37
aGVHD III-IV P = .02 P = .02 P = .57 P = .04 P = .04 P = .11 P = .67 P = .42
AA, n = 212 AA, n = 311 AA, n = 372 Neutral, n = 427 0, n = 212 0-1, n = 427 2, n = 160 No, n = 372
Bx, n = 409 AB, n = 251 AB, n = 215 Better, n = 135 1, n = 215 2+, n = 194 3, n = 362 Yes, n = 242
BB, n = 59 BB, n = 34 Best, n = 59 2, n = 151 4, n = 99
3+, n = 43
cGVHD P = .45 P = .17 P = .36 P = .18 P = .22 P = .36 P = .51 P = .93
AA, n = 237 AA, n = 350 AA, n = 419 Neutral, n = 485 0, n = 237 0-1, n = 485 2, n = 182 No, n = 432
Bx, n = 467 AB, n = 288 AB, n = 242 Better, n = 153 1, n = 248 2+, n = 219 3, n = 409 Yes, n = 272
BB, n = 66 BB, n = 43 Best, n = 66 2, n = 167 4, n = 113
3+, n = 52
Neutrophil engraftment P = .76 P = .56 P = .28 P = .68 P = .51 P = .71 P = .44 P = .38
AA, n = 242 AA, n = 356 AA, n = 426 Neutral, n = 493 0, n = 242 0-1, n = 493 2, n = 184 No, n = 439
Bx, n = 474 AB, n = 293 AB, n = 247 Better, n = 156 1, n = 251 2+, n = 223 3, n = 418 Yes, n = 277
BB, n = 67 BB, n = 43 Best, n = 67 2, n = 170 4, n = 114
3+, n = 53
Platelet engraftment P = .09 P = .57 P = .28 P = .48 P = .36 P = .23 P = .51 P = .42
AA, n = 240 AA, n = 354 AA, n = 423 Neutral, n = 490 0, n = 240 0-1, n = 490 2, n = 183 No, n = 437
Bx, n = 472 AB, n = 291 AB, n = 246 Better, n = 155 1, n = 250 2+, n = 222 3, n = 415 Yes, n = 275
BB, n = 67 BB, n = 43 Best, n = 67 2, n = 169 4, n = 114
3+, n = 53