Table 7.
Test accuracy for proximal compression ultrasound in patients with suspected recurrent lower extremity DVT
| Test result | No. of results per 1000 patients tested (95% CI) | No. of participants (studies) | Certainty of the evidence (GRADE) | |
|---|---|---|---|---|
| Prevalence 15%*† in patients suspected of having LE DVT | Prevalence 40%*† in patients suspected of having LE DVT | |||
| True positives | 137(120-144) | 364 (320-384) | 205 (1) | ⊕⊕◯◯Low‡ |
| False negatives | 13 (6-30) | 36 (16-80) | ||
| True negatives | 850(808-850) | 600 (570-600) | 205 (1) | ⊕⊕◯◯Low‡ |
| False positives | 0 (0-42) | 0 (0-30) | ||
| Inconclusive test results | 0 | 205 (1) | ||
| Complications arising from the diagnostic test | NA | |||
An interactive version of this table is available at: https://gdt.gradepro.org/presentations/#/isof/isof_466028d8-a7f3-444b-9245-78afb4162894-1582834752782?_k=b2zvrj.
Patient or population: Patients with suspected recurrent lower extremity deep vein thrombosis. Setting: Inpatient and outpatient. Pooled sensitivity: 0.91 (95% CI, 0.80-0.96). Pooled specificity: 1.00 (95% CI, 0.95-1.00).
Prevalence of recurrent VTE was estimated to be 13% (1 year) to 30% (10 years) based on the review (20% used in the table).61
Clinical PTP and D-dimer used to evaluate patients with suspected recurrent DVT, prevalence 44.8% (40% used in table).56
Certainty of evidence was downgraded twice for serious imprecision given the small population size from the 2 recurrent lower extremity DVT studies identified for analysis.