Table 1.

Overview of EOC Patients and Samples and of Established Organoid Lines

Patient/EOC Sample No.	Fresh/Cryo	EOC Typea	Patient Treatmentb	EOC Organoid Linec	Organoid Morphology	Passaging Time
1	fresh	malignant mixed mesonephric tumor IC2	PDS	–
2	fresh	HGSOC IVA	IDS	–
3	fresh	HGSOC IVB	PDS	EOC-O_1	cystic/low-cohesive	short-term
4	fresh	HGSOC IIIC	IDS	EOC-O_2	dense/cystic	long-term
5	fresh	HGSOC IIIC	IDS	–
6	fresh	HGSOC IVB	IDS	–
7	fresh	HGSOC IIIC	IDS	–
8	cryo	HGSOC IVB	IDS	–
9	fresh	LGSOC IVB	IDS	EOC-O_3	dense/low-cohesive	short-term
10	fresh	HGSOC IVB	TDS	EOC-O_4	dense	long-term
11	cryo	HGSOC IIIC	PDS	–
12	fresh	HGSOC IIIC	IDS	–
13A	fresh	HGSOC IVB (omentum)	IDS	–
13B	cryo	HGSOC IVB (ovary)	IDS	EOC-O_5	dense	short-term
14	fresh	clear cell ovarian cancer IIIA1(i)	PDS	EOC-O_6	dense/cystic	short-term
15	cryo	HGSOC IVB	IDS	EOC-O_7	cystic	long-term
16	cryo	HGSOC IVB	IDS	–
17	cryo	HGSOC IIIB	SDS	–
18	fresh	HGSOC IIIC	IDS	EOC-O_8	low-cohesive	long-term
19	fresh	HGSOC IVB	IDS	–
20	fresh	HGSOC IVB	IDS	–
21Ad	fresh	HGSOC IIIC (ovary)	IDS	EOC-O_9	cystic	long-term
21B	fresh	HGSOC IIIC (omentum)	IDS	–
21C	fresh	HGSOC IIIC (rectum)	IDS	–
22	cryo	mucinous cystadenocarcinoma IC1	PDS	EOC-O_10	cystic	short-term
23A	cryo	HGSOC IVB (ovary)	PDS	EOC-O_11	cystic	long-term
23B	cryo	HGSOC IVB (omentum)	PDS	–
24	cryo	HGSOC IVB	IDS	EOC-O_12	dense	short-term
25	cryo	HGSOC IIIC	IDS	–
26	cryo	LGSOC IIIC	PDS	EOC-O_13	dense/low-cohesive	short-term
27	cryo	HGSOC IIB	PDS	–

^aHGSOC, high-grade serous ovarian cancer; LGSOC, low-grade serous ovarian cancer. In case of additional out-of-the-ovary sampling from the same patient, the different surgical sites are specified.

^bIDS, interval debulking surgery; PDS, primary DS; SDS, secondary DS; TDS, tertiary DS.

^c–, no organoid derivation.

^dEventual healthy tissue organoids.