Table 2.
Comparison of covariates between patients with and without adequate IMN coverage.
| Characteristic | Total | ≥45 Gy | <45 Gy | p-value | |
|---|---|---|---|---|---|
| Number of patients | 138 | 10 | 128 | ||
| Cancer laterality | Right | 67 (48.55%) | 3 (30%) | 64 (50%) | 0.909 |
| Left | 71 (51.45%) | 7 (70%) | 64 (50%) | ||
| Height (cm) | Mean | 160.16 | 158.7 | 160.27 | 0.441 |
| SD | 5.54 | 4.79 | 5.59 | ||
| Body weight (kg) | Mean | 66 | 58.6 | 66.57 | 0.002 |
| SD | 8.83 | 4.485 | 8.84 | ||
| BMI | Mean | 25.74 | 23.36 | 25.93 | 0.010 |
| SD | 3.30 | 2.70 | 3.27 | ||
| BSA | Mean | 1.67 | 1.57 | 1.68 | 0.007 |
| SD | 0.13 | 0.05 | 0.13 | ||
| DAP (cm) | Mean | 10.01 | 9.71 | 10.04 | 0.438 |
| SD | 1.27 | 1.49 | 1.26 | ||
| DT (cm) | Mean | 23.25 | 22.71 | 23.29 | 0.043 |
| SD | 1.24 | 0.38 | 1.28 | ||
| RT/AP (%) | Mean | 43.21 | 42.77 | 43.25 | 0.796 |
| SD | 6.28 | 6.84 | 6.27 | ||
| Internal thoracic vessels, n | 2 | 128 (92.75%) | 9 (90%) | 119 (92.97%) | 0.728 |
| 3 | 10 (7.25%) | 1 (10%) | 9 (7.03%) | ||
| CTV volume (cm3) | Mean | 436.71 | 409 | 438.88 | 0.622 |
| SD | 138.16 | 90.2 | 141.24 | ||
| PTVIMN volume (cm3) | Mean | 29.44 | 28.92 | 29.48 | 0.748 |
| SD | 5.33 | 4.27 | 5.43 | ||
| IMNin (cm3) | Mean | 5.61 | 13.33 | 5.00 | 0.000 |
| SD | 4.88 | 3.54 | 4.45 | ||
| RIMNin (%) | Mean | 18.92 | 46.33 | 16.78 | 0.000 |
| SD | 15.93 | 11.80 | 14.14 | ||
| Irradiation technique, n | 3D-CRT | 48 (34.78%) | 5 (50%) | 43 (33.59%) | 0.112 |
| F-IMRT | 49 (35.51%) | 1 (10%) | 48 (37.50%) | ||
| I-IMRT | 41 (29.71%) | 4 (40%) | 37 (28.91) | ||
| SCF, n | Yes | 131 (94.93%) | 10 (100%) | 121 (94.53%) | 0.449 |
| No | 7 (5.07%) | 0 (0) | 7 (5.47%) | ||
| Cranial border (CTV), n | Clinical reference + second rib insertion | 65 (47.10%) | 4 (40%) | 61 (47.66%) | 0.642 |
| Caudal border of the clavicle head | 73 (52.90%) | 6 (60%) | 67 (52.34%) | ||
| Medial border (CTV), n | Midline | 33 (23.91%) | 5 (50%) | 27 (21.26%) | 0.190 |
| Sternal-rib junction | 78 (56.52%) | 3 (30%) | 75 (59.06%) | ||
| In between | 27 (19.57) | 2 (20%) | 25 (19.68%) | ||
| Posterior border (PTV), n | Intrapulmonary | 78 (56.52%) | 8 (80%) | 70 (54.69%) | 0.121 |
| Rib-pleural interface | 60 (43.48%) | 2 (20%) | 58 (45.31%) | ||
| Wedge shaped plate, n | Yes | 15 (31.25%) | 5 (50%) | 10 (23.26%) | 0.069 |
| No | 33 (68.75%) | 5 (50%) | 33 (76.74%) | ||
| Incident angles (°) | Mean | 52.64 | 52.3 | 52.66 | 0.993 |
BMI, body mass index; BSA, body surface area; CTV, clinical target volume; PTV, planning target volume; DT, thoracic transverse diameter; DAP, thoracic anteroposterior diameter; SCF, supraclavicular fossa; PTVIMN, planning target volume of IMN; IMNin, PTVIMN included in PTV.