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. 2020 Jan 29;7(2):577–587. doi: 10.1002/ehf2.12614

Table 4.

Univariate and multivariate Cox regression analyses with mortality as the dependent variable

Univariate analysis Multivariate analysis
Hazard ratio (95% confidence interval) P value Hazard ration (95% confidence interval) P value
Age 1.051 (0.999–1.106) per year 0.06
Chronic obstructive lung disease 2.99 (1.22–7.34) 0.02
Oral anticoagulation 2.73 (1.17–6.39) 0.02
eGFR 0.98 (0.97–0.99) per mL/min/1.73 m2 0.048
Left ventricular ejection fraction 0.95 (0.93–0.98) per % <0.001 0.96 (0.94–0.99) per % 0.01
Combined pre‐capillary and post‐capillary pulmonary hypertension 6.51 (2.81–15.08) <0.001 4.58 (1.89–11.09) 0.001
Mean aortic valve gradient 0.97 (0.94–1.00) per mmHg 0.06
Mitral regurgitation 2.27 (1.41–3.67) per grade 0.001
FEV1 0.97 (0.95–0.99) per % 0.003
TAVR vs. SAVR 2.70 (1.15–6.36) 0.02
ln BNP 1.90 (1.33–2.71) <0.001

BNP, B‐type natriuretic peptide; eGFR, estimated glomerular filtration rate; FEV1, forced expiratory volume within the first second; SAVR, surgical aortic valve replacement; TAVR, transcatheter aortic valve replacement.