Figure 2.
The electrophysiological properties of the atrial in wide‐type (WT) and myeloid differentiation protein 1 knock‐out mice 4 weeks after saline or aldosterone infusion. (A–D) Intra‐atrial conduction time (IACT) and effective refractory period (ERP) of the left atrium evaluated in the study using isolated perfused heart mice (n = 8). (E) Representative electrograms of atrial fibrillation (AF) induction after atrial burst pacing in the isolated perfused heart using Langendorff apparatus in a knock‐out (KO)‐Aldo mouse. (F,G) Inducibility and duration of AF in the study using isolated perfused heart (n = 12–13). Data are expressed as mean ± standard error of the mean. * P < 0.05 vs. wild‐type (WT)‐Sal group, # P < 0.05 vs. WT‐Aldo group, and § P < 0.1 vs. WT‐Aldo group.