Table 1.

Characteristics of wild‐type or myeloid differentiation protein 1 knock‐out mice 4 Weeks after saline/aldosterone infusion

Groups	WT‐Saline (n = 8)	KO‐Saline (n = 8)	WT‐Aldo (n = 8)	KO‐Aldo (n = 8)
BW (g)	21.56 ± 0.35	22.28 ± 0.31	22.81 ± 0.34	23.59 ± 0.44*
HW/BW (mg/g)	4.56 ± 0.06	4.48 ± 0.07	5.82 ± 0.09*	6.82 ± 0.16*,**
LW/BW (mg/g)	4.98 ± 0.06	5.08 ± 0.1	6.96 ± 0.17*	7.77 ± 0.21*,**
LW/TL (mg/g)	5.85 ± 0.07	6.09 ± 0.1	8.5 ± 0.12*	9.94 ± 0.15*,**
LVEDd (mm)	3.9 ± 0.08	3.83 ± 0.09	3.85 ± 0.1	3.96 ± 0.07
LVESd (mm)	2.18 ± 0.06	2.11 ± 0.07	2.15 ± 0.07	2.35 ± 0.13
LVEF (%)	81.63 ± 0.8	82.12 ± 0.95	80.13 ± 1.91	77.13 ± 2.95
LVFS (%)	44.38 ± 0.01	44.63 ± 0.01	43.88 ± 0.02	40.63 ± 0.03
LAD (mm)	1.55 ± 0.04	1.59 ± 0.04	1.56 ± 0.1	1.59 ± 0.07
Serum aldosterone levels (pg/mL)	235.3 ± 19.09	238.79 ± 15.13	438.47 ± 12.85*	458.48 ± 10.8*

Aldo, Aldosterone; BW, body weight; HW, heart weight; KO, knock‐out; LAD, left atrial diameter; LVEDd, left ventricle end‐diastolic dimension; LVEF, left ventricular ejection fraction; LVFS, left ventricular fractional shortening; LVESd, left ventricular end‐systolic diameter; LW, lung weight; TL, tibial length.

Data are expressed as Mean ± standard error of the mean.

^* P < 0.05 vs. WT‐Sal group.

^** P < 0.05 vs. WT‐Aldo group.