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Costunolide induces apoptosis of H1299 lung cancer cells in vitro. (A) H1299 cells were treated with costunolide for 48 h and apoptosis was detected via fluorescence-activated cell sorting. Representative images are displayed. (B) Data are presented as the mean ± standard deviation (n=3). Differences between concentrations were tested using one-way ANOVA and Tukey's post hoc tests. *P<0.05, **P<0.01; NS, not significant. Con, control.
