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. 2020 Mar 26;43(6):1986–1994. doi: 10.3892/or.2020.7566

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Copyright: © Wei et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Costunolide decreases the invasive ability of H1299 lung cancer cells in vitro. (A) The invasive ability of H1299 cells was detected via Transwell assay. Following treatment of H1299 cells with different concentrations of costunolide for 48 h, the number of invaded cells decreased in a dose-dependent manner. (B) Quantitative results presented as the mean ± standard deviation (n=3). (C) Following treatment of H1299 cells with 24.0 µM costunolide for 24 and 48 h, the number of invaded cells decreased in a time-dependent manner. (D) Quantitative results presented as the mean ± standard deviation (n=3). Differences between (B) concentrations and (D) times were tested using one-way ANOVA and Tukey's post hoc tests. *P<0.05, **P<0.01. Con, control.