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. 2020 Mar 19;43(6):1819–1830. doi: 10.3892/or.2020.7554

Figure 3.

Figure 3.

Acetylation and succinylation of H2A.X-complexes may affect DDR in breast cancer. (A) Biological process analysis of H2A.X-complexes; the first eight entries with a corrected P-value<0.05 are presented. (B) Biological process entries associated with DDR (P<0.05) of proteins with significantly higher expression levels in breast cancer tissues (fold change≥1.5 compared with adjacent normal tissues). (C) Biological process entries associated with DDR (P<0.05) of proteins with significantly lower expression levels in breast cancer tissues (fold change≤1/1.5 compared with adjacent normal tissues). (D and E) Relative expression levels of proteins corresponding to B and C in breast cancer tissues and adjacent normal tissues. H2A.X, histone H2A.X; DDR, damage response.