Table 1.

Some of the ADMET properties/parameters and their acceptable ranges.

Property name	Notation	Default range
MW	Molecular weight	50–500
iLOGP	octanol/water partition coefficient	-2–10
TPSA	Topological Polar Surface Area	20–130
HBA	Number of H-Bond acceptors	0–10
HBD	Number of H-bond Donors	0–5
RB	Rotatable bonds	0–5
nheavy atoms	Number of heavy atoms	15–50
logP	Lipophilicity of the compound	-0.7–5.0
MR	Molar refractivity	40–130