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. 2020 Jan 15;9(4):661–677. doi: 10.1016/j.jcmgh.2020.01.003

Figure 4.

Figure 4

Integrin and chemokine receptor surface expression differ between blood and peritoneal MAIT cells. Surface expression of (A) alpha 4 integrin (n = 3–6), (B) beta 7 integrin (n = 6–12), and (C) CCR6 (n = 7) on circulating CD3+ Vα7.2+ CD161hi MAIT (cMAIT) and peritoneal CD3+ Vα7.2+ CD161hi MAIT (pMAIT) cells from healthy controls (HC) and patients with decompensated liver cirrhosis (DLC) in absence of SBP are shown. Surface expression of (D) alpha E integrin (n = 5–12), (E) CCR5 (n = 9–12), and (F) CXCR3 (n = 11–12) on CD3+ Vα7.2+ CD161hi cMAIT and CD3+ Vα7.2+ CD161hi pMAIT cells from HC, patients with DLC in absence of SBP, and in noncirrhotic patients undergoing CAPD. Surface expression of (G) CCR5 (n = 10–12) and (H) CXCR3 (n = 8–12) on CD3+ Vα7.2+ CD161hi pMAIT cells from patients with DLC in absence or presence of SBP. **P < .01, ***P < .001 in Wilcoxon signed-rank test (paired samples) and Mann-Whitney U test (unpaired samples). P value from Mann-Whitney U test.