TABLE 2.

Next Generation Sequencing Data on Nonneoplastic Brain Tissue

Chromosome	Position	Reference	Variant	Allele Call	Type	Allele Source	Gene ID
Father
Chr 11	534242	A	G	Heterozygous	SNP	Novel	HRAS
Chr4	1807894	G	A	Homozygous	SNP	Novel	FGFR3
Chr5	1494533049	G	A	Heterozygous	SNP	Novel	CSFIR
Chr7	55249063	G	A	Homozygous	SNP	Novel	EGFR
Chr10	43613843	G	T	Homozygous	SNP	Novel	RET
Chr13	28610183	A	G	Homozygous	SNP	Novel	FLT3
Patient
Chr 11	534242	A	G	Heterozygous	SNP	Novel	HRAS
Chr4	1807894	G	A	Homozygous	SNP	Novel	FGFR3
Chr5	149433596	TG	GA	Homozygous	MNP	Novel	CSFIR
Chr7	55249063	G	A	Heterozygous	SNP	Novel	EGFR
Chr10	43613843	G	T	Homozygous	SNP	Novel	RET
Chr13	28610183	A	G	Heterozygous	SNP	Novel	FLT3

Common novel mutations identified in nonneoplastic brain tissue shared between the patient and his father are shown. Nonneoplastic tissue from the sister was not available. Of note, HRAS is the only mutation identified in both neoplastic and nonneoplastic tissues for the patient and his father.