FIG 2.
B6 and DO mice vaccinated subcutaneously with M. bovis BCG clear bacteria from organs at similar rates. Groups of five B6 and DO male mice were vaccinated subcutaneously with 105 BCG. Animals were euthanized 4 weeks after vaccination, and organs were extracted, homogenized, and plated to enumerate BCG CFU. This experiment was repeated twice, and results combined from the two experiments are shown. Dots represent BCG CFU in individual animals, and lines represent median CFU per group. Pairwise comparisons between B6 and DO mice for each organ did not detect significant differences (P > 0.05 by Student's t test for all combinations). L.O.D., limit of detection.