Table 2.
Characteristics of included studies of diarrhea.
| References | Study design | Patient number | Age | Sex (m/f) | Time to symptom (months) | Resolution of diarrhea with HBO | No improvement n/N (%) | Resolution of diarrhea without HBO | No improvement n/N (%) | Dose of HBO (ATA) | Sessions of HBO | Follow-up after HBO (months) | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Complete recovery n/N (%) | Partial recovery n/N (%) | Complete recovery n/N (%) | Partial recovery n/N (%) | |||||||||||
| Clarke et al. (28) | RCT | 119 | – | Both (-) | – | 5/63 (8%) | 51/63 (81%) | 7/63 (11%) | 0/56 (0%) | 35/56 (62.5%) | 21/56 (37.5%) | 2.0 vs. 1.1 | 30 and additional 10 treatments | 25.1 |
| Glover et al. (18) | RCT | 39 | 62 | Both (-) | – | 14/23 (61%) | 9/23(39%) | 12/16 (75%) | 4/16 (25%) | 2.4 vs. 1.3 | 40 | 13.2 | ||
| Jones et al. (31) | Retrospective | 5 | 65 | <24 | 1/5 (20%) | 3/5 (60%) | 1/5 (20%) | – | – | – | 2.4 | 40 | 25 | |
| Marshall et al. (32) | Retrospective | 12 | 65 | Both (-) | – | 4/12 (33%) | 3/12 (25%) | 5/12 (42%) | – | – | – | 2.36 | 30 and additional 6–30 treatments | 20 |
| Warren et al. (37) | Retrospective | 5 | 68 | Both (4/1) | 8.4 | 4/5 (80%) | 1/5 (20%) | 0/5 (0) | – | – | – | 2.0 or 2.36 | 32 | 12 |
| Woo et al. (38) | Retrospective | 8 | 72 | Both (-) | - | 2/8 (25%) | 2/8 (25%) | 4/8 (50%) | – | – | – | 2.0 | 24 | 14 |
RCT, randomized controlled trial; HBO, hyperbaric oxygen.