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. 2020 Apr 3;2020:4398924. doi: 10.1155/2020/4398924

Table 3.

Scoring criteria of immunohistochemistry assay with the specific antibodies.

Staining positive cells Staining intensity Final score product
Groups Percent (%) Score 1 Intensity Score 2 Score 1 × Score 2 Score 3
p53
 C <5% 0 Absent 0 0-1 0(-)
 Cd 51%-75% 3 Strong 3 9-12 3+(+++)
 Cd+OL 6%-25% 1 Weak 1 2-4 1+(+)
Bcl-2
 C 51%-75% 3 Strong 3 9-12 3+(+++)
 Cd 6%-25% 1 Weak 1 2-4 1+(+)
 Cd+OL 26%-50% 2 Moderate 2 5-8 2+(++)
COX-2
 C <5% 0 Absent 0 0-1 0(-)
 Cd 51%-75% 3 Strong 3 9-12 3+(+++)
 Cd+OL 6%-25% 1 Weak 1 2-4 1+(+)