Table 1.
Clinical details of infants aged less than 12 months treated for aggressive brain tumors.
| Patient n | Age at diagnosis (days) | Histology |
Resection R0 (gross total resection) R2 (partial resection) |
Genetic analysis | Outcome |
|---|---|---|---|---|---|
| 1 | 70 | AA | R2 | NO | Alive at 87 months |
| 2 | 1 | GBM | R0 | NO | Alive at 67 months |
| 3 | 176 | AA | R0 | NTRK fusion | Alive at 71 months |
| 4 | 141 | AA | R2 | NO | Alive at 56 months |
| 5 | 1 | AA | R2 | Somatic trisomy 8 – mosaicism | Alive at 36 months |
| 6 | 1 | AT/RT | R2 | Germline SMARCB1/INI1 mutation | DOD at 18 months |
| 7 | 279 | CNS embryonal tumor NOS | R2 | NO | Alive at 38 months |
| 8 | 1 | CNS embryonal tumor NOS | R2 | NO | Alive at 16 months |
| 9 | 60 | AT/RT | R2 | Germline SMARCB1/INI1 mutation | DOD at 6 months |
| 10 | 52 | GBM | R2 | NO | DOD at 25 months |
AA, Anaplastic Astrocytoma; GBM, glioblastoma; AT/RT, Atypical Teratoid Rhabdoid Tumor; DOD, Dead of Disease, R0, gross total resection (a resection without visual residual enhancing tumor), R2, partial resection (a resection of only part of the tumor).